ETIOLOGY AND MOLECULAR GENETIC IDENTIFICATION OF CONGENITAL FEMALE GENITAL TRACT ANOMALIES
Keywords:
congenital anomalies of genital development, bicornuate uterus, genetics, diagnosis, aplasia of uterus and vaginaAbstract
Congenital malformations of the reproductive system organs represent a significant factor in female infertility and are traditionally associated with an unfavorable obstetric prognosis. Although the implementation of modern assisted reproductive technologies (ART) has substantially expanded therapeutic possibilities, the effectiveness of these programs is largely determined by the timely verification of the anomaly. Optimization of reproductive outcomes requires not only early diagnosis of malformations but also the development of rational patient management algorithms, including targeted endometrial preparation for implantation
References
Dietrich J.E., Millar D.M., Quint E.H. Obstructive reproductive tract anomalies // J. Pediatr. Adolesc. Gynecol. 2014. Vol. 27, N 6. P. 396–402. DOI: https://doi.org/10.1016/j.jpag.2014.09.001 Epub 2014 Sep 11. PMID: 25438708.
Deans R., Berra M., Creighton S.M. Management of vaginal hypoplasia in disorders of sexual development: surgical and non-surgical options // Sex Dev. 2020. Vol. 4. P. 292-299.
Di Spiezio Sardo A., Florio P., Nazzaro G., Spinelli M., Paladini D., Di Carlo C. et al. Hysteroscopic outpatient metroplasty to expand dysmorphic uteri (HOME-DU technique): a pilot study // Reprod. Biomed. Online. 2015. Vol. Тридцать, N 2. P. 166– 174.
Fedele L., Frontino G., Restelli E., Ciappina N., et al. Creation of a neovagina by Davydov’s laparoscopic modified technique in patients with Rokitansky syndrome// Am. J. Obstet. Gynecol. 2020. Vol. 202, N 1. P. 33.e1–e6.
Fedele L., Motta F., Frontino G., Restelli E., et al. Double uterus with obstructed hemivagina and ipsilateral renal agenesis: pelvic anatomic variants in 87 cases // Hum. Reprod. 2013 Jun. Vol. 28, N 6. P. 1580–1583.
Heinonen P. Pregnancies in women with uterine malformation, treated obstruction of hemivagina and ipsilateral renal agenesis // Arch. Gynecol. Obstet. 2013. Vol. 287, N 5. P. 975–978
Keser A., Bozkurt N., Taner O.F. et al. Treatment of vaginal agenesis with modified Abbe-McIndou technique: long-term follow-up in 22 patients // Eur. J. Obstet. Gynecol. Reprod. Biol. 2015. Vol. 121. P. 110.
Toublanc J.E., Roger M., Chaussain J.L. Etiologies of late puberty. 2021. -Vol. 36. — P.136-140.
Vetter U., Fedarko N.S., Yong M.F. et al. Biglycan sythesis in fibroblasts of patients with Turner syndrome and other sex chromosome anomalies//1.: Basicand clinical approach to Turner syndrome. - Amsterdam: Elsevier Science Pub, 2023.-P. 143-146.
Warming L., Raun P., Nielsen T. Safety and aficacy of drospirenone in a continuous combination with 17b-estradiol for prevention of osteoporosis. -Climacteric. 2014. - №7. - P. 103-107.
Wattiez A. et. al. Laparoscopic operations for stress incontinence. Endoscopy for diagnosis and treatment of uterine pathology. Moscow. -2017. - P. 165.
Wilson J.D. The Role of Androgens in Male Gender Role Behavior // Endocr. Rev. 2019. - Vol.20, №5.- P. 726-737.
Shakhanova S. et al. MELANOMA OF THE SKIN AND PREGNANCY //Eurasian Journal of Academic Research. – 2023. – T. 3. – No. 3. – pp. 120-128.
Abdurakhmonov Jurabek , Rahimov Nodir , Shakhanova Shakhnoza . Modern view on ascite in ovarian cancer. Journal of Biomedicine and Practice . 2022, vol . 7, issue 4, pp . 130-139
Jasur Rizayev Alimjanovich , Larisa Rubenovna Agababyan , Anvar Ibragimovich Kamalov . AYOLLARDA TUG'RUQDAN KEYINGI QON KETISHLARNI OLDINI OLISH VA ULARGA QARSHI KURASHISH BO'YICHA KO'RSATILAYOTGAN XIZMATLAR SIFATINING MONITORINGINI TASHKIL ETISH // Oriental Renaissance: Innovative, educational, natural and social sciences Volume 1_ ISSUE 10 202 1 p.m. 166-169
Alimjanovich JR, Agababyan LR, Kamalov AI Prevention and Treatment of Postpartum Hemorrhage //CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. – 2021. – T. 2. – No. 4. – S. 204-209.
Rizaev Jasur Alimjanovich , Agababyan Larisa Rubenovna , Davlatova Aziza, Ahmedova Aziza Tayirovna , Rasulova Feruza Golibovna , The state of the oral cavity in pre-pregnant women, Journal of reproductive health and uronephrology research 2023, vol. 4, issue 4, pp7-11
Rizaev J. A., Nazarova N. S., Vohidov E. R. HOMILADOR AYOLLARDA PARODONT KASALLIKLARI RIVOJLANISHINING PATOGENETIK JIHATLARI //Журнал гуманитарных и естественных наук. – 2024. – №. 11 [2]. – С. 104-107.