СОВРЕМЕННОЕ СОСТОЯНИЕ ПРОБЛЕМЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ПАРОДОНТА У ПАЦИЕНТОВ С СОМАТИЧЕСКОЙ ПАТОЛОГИЕЙ (РЕВМАТОИДНЫМ АРТРИТОМ): ПАТОГЕНЕТИЧЕСКИЕ ВЗАИМОСВЯЗИ И КЛИНИЧЕСКИЕ ПОДХОДЫ
Ключевые слова:
пародонтит, ревматоидный артритАннотация
Настоящая обзорная статья посвящена комплексному анализу патогенетической, клинической и диагностической взаимосвязи между воспалительными заболеваниями пародонта и значимой системной патологией: ревматоидным артритом (РА).
Библиографические ссылки
Borgnakke W. S. Periodontal disease and systemic health: An update for medical practitioners / W. S. Borgnakke // Annals Academy of Medicine Singapore. – 2026. – URL: https://annals.edu.sg/periodontal-disease-and-systemic-health-an-update-for-medical-practitioners/.
Löe H. Correlation between aging, periodontal diagnoses and systemic health / H. Löe // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC12645722/
Kim J. The Relationship Between Periodontitis and Systemic Diseases / J. Kim, S. Amar // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC3644469/.
Dietrich T. The interrelationship between periodontal disease and systemic health / T. Dietrich, P. Sharma, C. Walter // White Rose Research Online. – 2026. – URL: https://eprints.whiterose.ac.uk/id/eprint/229741/1/s41415-025-8642-2.pdf.
Schulze-Späte U. Effect of Periodontal Treatment on HbA1c among Patients with Diabetes / U. Schulze-Späte // DNB. – 2026. – URL: https://d-nb.info/1255364882/34.
Baeza, M. The Bidirectional Relationship between Periodontal Disease and Diabetes Mellitus / M. Baeza, A. Morales, C. Cisterna [et al.] // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC9954907/.
Koziel J. Porphyromonas gingivalis and rheumatoid arthritis / J. Koziel, P. Mydel, J. Potempa // PubMed. – 2026. – URL: https://pubmed.ncbi.nlm.nih.gov/31268867/.
Kaur S. The Link Between Periodontal Disease and Rheumatoid Arthritis: An Updated Review / S. Kaur, S. Bright, S. M. Proudman [et al.] // ResearchGate. – 2026. – URL: https://www.researchgate.net/publication/259882801.
Routsias J. G. Autopathogenic correlation of periodontitis and rheumatoid arthritis / J. G. Routsias, J. D. Goules, A. Goules [et al.] // Rheumatology. – 2026. – URL: https://academic.oup.com/rheumatology/article-pdf/50/7/1189/5065063/ker090.pdf.
Konig M. F. Defining the role of Porphyromonas gingivalis peptidylarginine deiminase in rheumatoid arthritis / M. F. Konig, F. Andrade // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC4368502/.
Eriksson K. Implications for autoimmunity in rheumatoid arthritis / K. Eriksson, L. Nise, T. Katsila [et al.] // Annals of the Rheumatic Diseases. – 2026. – URL: https://ard.bmj.com/content/75/6/1255.
Lundberg K. Citrullination as a plausible link to periodontitis, rheumatoid arthritis and smoking / K. Lundberg, N. Wegner, T. Yucel-Lindberg [et al.] // Taylor & Francis Online. – 2026. – URL: https://www.tandfonline.com/doi/full/10.1080/20002297.2018.1487742.
Gomez-Bañuelos E. Impact of Protein Citrullination by Periodontal Pathobionts on Oral and Systemic Health / E. Gomez-Bañuelos, F. Andrade // MDPI. – 2026. – URL: https://www.mdpi.com/2077-0383/13/22/6831.
Ceccarelli F. Periodontal Pathogens Correlate with Rheumatoid Arthritis Disease Activity / F. Ceccarelli, M. Saccucci, R. Di Giorgio [et al.] // MDPI. – 2026. – URL: https://www.mdpi.com/2304-6767/13/5/214.
Williams R. C. Periodontal disease and systemic conditions: a bidirectional relationship / R. C. Williams // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC2443711/.
Tsukasaki M. Osteocyte RANKL Drives Bone Resorption in Mouse Ligature-Induced Periodontitis / M. Tsukasaki, N. Komatsu, K. Konakai [et al.] // Journal of Bone and Mineral Research. – 2026. – URL: https://academic.oup.com/jbmr/article/38/10/1521/7610377.
Gümüş P. Periodontal disease influences osteoclastogenic bone markers in patients with rheumatoid arthritis / P. Gümüş, A. S. Buduneli, S. Cetinkalp [et al.] // PLOS ONE. – 2026. – URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197235.
Cruz-Tapias P. HLA-Disease Associations in Rheumatoid Arthritis / P. Cruz-Tapias, J. Castiblanco, J. M. Anaya // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC5643023/.
Yassine F. Current Understanding of an Emerging Role of HLA-DRB1 Gene in Rheumatoid Arthritis / F. Yassine, S. S. Al-Swailem, A. Al-Swailem // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC7291248/.
Molitor J. A. Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Mechanisms / J. A. Molitor // MDPI. – 2026. – URL: https://www.mdpi.com/1422-0067/20/18/4541.
Zhao X. How RA Associated HLA-DR Molecules Contribute to the Pathogenesis of Rheumatoid Arthritis / X. Zhao, H. Chen, X. Lin [et al.] // Frontiers in Immunology. – 2026. – URL: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.930112/full.
Laugisch O. Relationship Between Rheumatoid Arthritis and Periodontal Status / O. Laugisch, A. Wong, A. Suter [et al.] // MDPI. – 2026. – URL: https://www.mdpi.com/2077-0383/14/1/10.
D'Aiuto F. Does periodontal treatment improve rheumatoid arthritis disease activity? / F. D'Aiuto, N. Gkranias, D. Bhowmick [et al.] // Oxford Academic. – 2026. – URL: https://academic.oup.com/rheumap/article/6/2/rkac061/6670638.
Jonsson M. V. Citrullinated protein antibodies, but not with the onset of rheumatoid arthritis / M. V. Jonsson, K. G. Sunstad, S. S. Hellvard [et al.] // RMD Open. – 2026. – URL: https://rmdopen.bmj.com/content/rmdopen/11/1/e005111.full.pdf.
Monsarrat P. The effect of periodontal treatment on patients with rheumatoid arthritis: The ESPERA randomised controlled trial / P. Monsarrat, J. N. Vergnes, C. Cantagrel [et al.] // ResearchGate. – 2026. – URL: https://www.researchgate.net/publication/331370467.
Zhu Y. The role of HbA1c in the bidirectional relationship between periodontitis and diabetes / Y. Zhu, L. Zhang, X. Wang // Frontiers in Nutrition. – 2026. – URL: https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1606223/full.
Preshaw P. M. Chronic Inflammation and Glycemic Control: Exploring the Link / P. M. Preshaw, J. J. Taylor // MDPI. – 2026. – URL: https://www.mdpi.com/2304-6767/13/3/100.
Noh J. Multi-dimensional role of AGEs in periodontitis / J. Noh, S. H. Kim, J. Y. Lee // Frontiers in Immunology. – 2026. – URL: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1643685/full.
Sczepanik F. S. C. Role of oxidative stress in the relationship between periodontitis and systemic diseases / F. S. C. Sczepanik, M. L. Grossi, M. Casati [et al.] // PubMed Central (PMC). – 2026. – URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10369007/.
