ORAL ALLERGY SYNDROME IN CHILDREN: WAYS OF SOLUTIONS
Keywords:
children, oral allergy syndrome, allergen-specific immunotherapyAbstract
Oral allergic syndrome (OAS, oral allergic syndrome) is a common problem in patients with sensitization to birch. The aim of the study is to establish the clinical effectiveness of the formation of tolerance to fruits and vegetables under the influence of ASIT by the allergen of birch pollen. Children (n=134) aged from 5 to 16 years (7.18±2.52 years) with OAS and respiratory allergy to birch pollen with sensitization to the Bet v1 molecule were given a three-year course of ASIT with the allergen "Staloral ® " "Birch pollen allergen". In 88.81% (n=119) of patients, it was possible to achieve full or partial tolerance of fresh vegetables and fruits without the occurrence of acute allergic symptoms on the mucous membrane of the oral cavity and pharynx (p=0.000). There was a decrease in the intensity and duration of respiratory symptoms during the pollination season, the need for pharmacotherapy after a full course of ASIT.
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