THE ROLE OF RENAL DYSFUNCTION AS AN INDEPENDENT PREDICTOR OF THE PROGNOSIS OF ACUTE MYOCARDIAL INFARCTION IN PEOPLE OF WORKING AGE

Authors

  • KHASANJANOVA Farida Odylovna
  • MAMATOVA Nargiza Toirjonovna

Keywords:

острый коронарный синдром, почки, ЭКГ, эхокардиография, СКФ и др

Abstract

This scientific paper analyzes the role of renal dysfunction as a prognostic predictor of cardiovascular death in patients with acute coronary syndrome of working age. The study included 122 patients with ACS aged 22 to 59 years who were hospitalized at the Samarkand regional branch of the Republican Specialized Scientific and Practical Medical Center of Cardiology in the departments of acute coronary syndrome (ACS) and coronary heart disease (CHD). All patients underwent a general clinical examination (anamnesis collection, anthropometric and physical examination of the patient, measurement of blood pressure, heart rate), laboratory and instrumental studies, which included clinical blood tests, biochemical blood analysis, troponin I, T, MB-CK, GFR, ECG, holter ECG, echocardiography upon admission and in dynamics on the 1st, 4th and 7th day of admission. With a decrease in GFR of less than 60 ml/min, it affects mortality from cardiovascular causes in patients with STEMI, but does not affect the prognosis in patients with STEMI. The widespread introduction of the GFR calculation method will allow timely detection of even a moderate violation of the filtration function of the kidneys and make adjustments to the patient's therapy, thereby reducing the number of adverse outcomes.

References

Aghababyan I. R. va boshkalar. Yurak ishemik kasalligi bo'lgan keksa yoshdagi bemorlarni yukori technologist usullar bilan davolash //Journal of Cardiological Research. - 2022. – Vol. 3. – No. 4. (in Uzb).

Belyalov F.I. Acute coronary syndrome and impaired renal function. Rational pharmacotherapy in cardiology 2016;12(1). pp. 71-76. (in Russ.).

Belyalov F.I. "Ischemic heart disease and impaired renal function." Rational pharmacotherapy in cardiology 13.3 (2017): 409-415. (to Russ.).

Zykov M.V. Clinical and prognostic significance of markers of renal dysfunction in patients with acute coronary syndrome with various treatment strategies. Presentation. 2016, pp. 4-5. (in Russ.).

Evseeva M. V. Et al. Impaired renal function in patients with myocardial infarction with concomitant type 2 diabetes mellitus //Therapeutic archive. - 2015. – vol. 87. – No. 1. – pp. 105-108. (in Russ.).

Nizamov H. S. The results of implantation of valve-containing frameless tricuspid conduits in the correction of congenital heart defects //Bulletin of the National Academy of Medical Sciences named after AN Bakulev RAMS. Cardiovascular diseases. – 2021. – vol. 22. – No. 3. – pp. 332-338. (in Russ.).

Nizamov H. Sh. Et al. Pandemic features of chronic heart failure in young patients //Periodical Journal of Modern Philosophy, Social Sciences and Humanities. – 2023. – vol. 17. – pp. 155-158. (in Russian).Низамов, Х. Ш. И др. Сравнительный анализ эффективности оральных антикоагулянтов при неклапанной форме фибрилляции предсердий. European Journal of Interdisciplinary Research and Development, 202315, 244-247. (in Russ.).

Rizaev J. A. et al. Modern trends in the prevalence and outcome of cardiovascular diseases among the population of the Republic of Uzbekistan //Journal of cardiorespiratory research. – 2023. – Vol. 1. – No. 1. – pp. 18-23. (in Russ.).

Saidov M. A. et al. Evaluation of the effectiveness of conservative treatment after coronary artery bypass grafting //Periodica Journal of Modern Philosophy, Social Sciences and Humanities. – 2023. – Vol. 17. – pp. 166-171. (in Russ.).

Saidov, M. A., et al. Characteristic features of myocardial contractile dysfunction during surgical correction of patients with coronary heart disease. European Journal of Interdisciplinary Research and Development, 202316, 32-37. (in Russ.).

Seitmaganbetova N.A. et al. The state of renal function in patients with acute coronary syndrome: a retrospective study. 62 (1) 2020 West Kazakhstan Medical Journal. (in Russ.).

Khasanjanova F. O. et al. Adverse risk factors affecting the outcome of treatment of patients with acute coronary syndrome with ST segment elevation //Avicenna. – 2019. – No. 34. – pp. 4-6. (in Russ.).

Khasanjanova F. O. et al. The role of changes in markers of cardiomyocyte necrosis in patients with myocardial infarction depending on age //Current scientific research in the modern world. - 2018. – No. 10-6. – pp. 42-45. (in Russ).

Khasanzhanova F. O. and other factors adversely affecting the outcome of treatment of patients with acute coronary syndrome in young and old age //Problems of modern science and education. – 2019. – №. 11-1 (144). – Pp. 94-97. (in Russ).

Khasanjanova F. O. et al. Analysis of the clinical course of unstable variants of angina pectoris in men at a young age //Journal of cardiorespiratory research. – 2022. – №. SI-2. (in Russ).

Khasanjanova F. O. et al. The role of the IL-1β 3953 C/T gene in the development of unstable variants of angina pectoris in men at a young age, depending on cytokine status //Journal of cardiorespiratory research. – 2021. – Vol. 1. – No. 4. – pp. 63-66. (in Russ).

Khasanjanova, F. O. et al. (). The Effectiveness Of Thrombolytic Therapy In Patients With Acute Coronary Syndrome With ST Segment Elevation In Young People. Central Asian Journal of Medical and Natural Science, 2023, 4(2), 632-636. (in Russ).

Khilchuk A.A. Methods of early diagnosis of contrast-induced acute renal injury after X-ray endovascular interventions in acute coronary syndrome without ST segment elevation electrocardiogram. Dissertation 2021 Pp. 4-5. (in Russ).

JA Rizaev , I. R. Agababyan , YAIsmoilova ACTIVITIES OF CLINICS SPECIALIZING IN THE TREATMENT OF PATIENTS WITH CHRONIC HEART DISEASE IN THE WORLD (REFERENCES). Journal of Biomedicine and Practice. 2021, vol. 6, issue 6, pp. 184-191

Shilyaeva N.V. Prognostic value of myocardial fibrosis and renal dysfunction in patients with chronic heart failure of ischemic etiology. Dissertation. Samara 2019, pp. 4-5. (in Russ).

Published

2024-12-23