PREVALENCE OF CERVICAL CANCER IN UZBEKISTAN: INCIDENCE AND MORTALITY
Keywords:
Cervical cancer, incidence, mortalityAbstract
Objective: To analyze the main statistical indicators of cervical cancer in the Republic of Uzbekistan over the past 15 years. Methods: The materials and methods of the study were the data from the state statistical report for the period 2010-2024 ("Information on malignant neoplasms" form-7). Results: In the Republic of Uzbekistan, cervical cancer takes the fourth place in the overall structure of oncological morbidity, behind breast cancer, colorectal cancer and stomach cancer. The study over 15-year period showed that there were registered 23 668 new cases of cervical cancer (6.9%), out of all malignant neoplasms. Over the past 15 years, the incidence rate of cervical cancer has tended to increase from 8,7 in 2010 to 11,1 in 2024 per 100,000 female population. In the Republic of Uzbekistan, the majority of patients with cervical cancer were aged 45-64 years (61.5%). From 2010 to 2024, 12 412 women died from cervical cancer in the Republic, with the mortality rate per 100,000 female population being 4,4 in 2010 and 4,9 in 2024. Conclusions: Based on the study, it can be concluded that cervical cancer has an increasing incidence in the Republic of Uzbekistan and is a leading cause of mortality among the female population, which requires timely decisions.
References
Lawson H.W, Henson R, Bobo JK, Kaeser MK. Implementing recommendations for the early detection of breast and cervical cancer among low-income women. MMWR Recomm Rep. 2000 Mar 31;49(RR-2):37-55. PMID: 15580731.
IARC/WHO. Uzbekistan – Cervical Cancer Elimination Profile, March 2025
Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229‐263.
Filho A.M, Laversanne M, Ferlay J, Colombet M, Piñeros M, Znaor A, Parkin DM, Soerjomataram I, Bray F. The GLOBOCAN 2022 cancer estimates: Data sources, methods, and a snapshot of the cancer burden worldwide. Int J Cancer. 2025 Apr 1;156(7):1336-1346. doi: 10.1002/ijc.35278. Epub 2024 Dec 17. PMID: 39688499.
Rim C.H. et al. Comparison of Breast Cancer and Cervical Cancer in Uzbekistan and Korea: The First Report of the Uzbekistan–Korea Oncology Consortium. – Asian Pacific Journal of Cancer Prevention, 2022. – Vol. 23(10). – P. 3367–3374.
Ryzhov A, Corbex M, Piñeros M, Barchuk A, Andreasyan D, Djanklich S, Ghervas V, Gretsova O, Kaidarova D, Kazanjan K, Mardanli F, Michailovich Y, Ten E, Yaumenenka A, Bray F, Znaor A. Comparison of breast cancer and cervical cancer stage distributions in ten newly independent states of the former Soviet Union: a population-based study. Lancet Oncol. 2021 Mar;22(3):361-369. doi: 10.1016/S1470-2045(20)30674-4. Epub 2021 Feb 5. PMID: 33556324; PMCID: PMC8014987.
Sattorov A.Kh. Statistics and prognosis of cervical cancer in Uzbekistan over the past 10 years // Journal of modern medicine No. 2 (9), 2025. P 425-433. file:///C:/Users/Statistika/Downloads/_.._files_681efd640fbdb%20(1).pdf. (in Russ)
State statistical reporting forms of the Ministry of Health of the Republic of Uzbekistan "Information on malignant neoplasms" - form № 7 for 2010-2024. (in Russ)
The state of oncological care for the population of the Republic of Uzbekistan in 2023 / edited by M.N. Tillashaykhov, Sh.N. Ibragimov, S.M. Djanklich. - Tashkent: Halk Publishing House, 2024. - 178 p. (in Russ)
The state of oncological care for the population of the Republic of Uzbekistan in 2024 / edited by M.N. Tillashaykhov, Sh.N. Ibragimov, S.M. Djanklich. - Tashkent: Halk Publishing House, 2025. - 184 p. (in Russ)
Wang J, Lv H, Xue Z, Wang L, Bai Z. Temporal Trends of Common Female Malignances on Breast, Cervical, and Ovarian Cancer Mortality in Japan, Republic of Korea, and Singapore: Application of the Age-Period-Cohort Model. Biomed Res Int. 2018 Mar 21;2018:5307459. doi: 10.1155/2018/5307459. PMID: 29750160; PMCID: PMC5884400.
Znaor A, Ryzhov A, Losada ML, Carvalho A, Smelov V, Barchuk A, Valkov M, Ten E, Andreasyan D, Zhizhilashvili S, Dushimova Z, Zhuikova LD, Egorova A, Yaumenenka A, Djanklich S, Tril O, Bray F, Corbex M. Breast and cervical cancer screening practices in nine countries of Eastern Europe and Central Asia: A population-based survey. J Cancer Policy. 2023 Dec;38:100436. doi: 10.1016/j.jcpo.2023.100436. Epub 2023 Aug 5. PMID: 37544479; PMCID: PMC10695765.
Alkhathami, A. G., Altalbawy, F. M. A., Rizaev, J. A., Jeddoa, Z. M. A., & Jabir, M. S. (2025). An overview of lncRNA GAPLINC's role in human cancer growth and metastasis. Archives of Biochemistry and Biophysics, 110506.
Rizaev Jasur , Norbutayev Alisher, Murtazayev Alisher . Modern methods for detecting oral cavity defects in hemoblastosis , detecting the degree of damage and prediction of the clinical current. Journal of Biomedicine and Practice. 2021, vol. 6, issue 5, pp. 45-51
Shakhanova, S. S., Abdurakhmonov, J. A., & Rakhimov, N. M. (2023). Targeted therapy in the palliative treatment of platinum-resistant recurrent ovarian cancer complicated by ascites. The American Journal of Medical Sciences and Pharmaceutical Research, 5(8), 1.
Rizaev, J. A., Rahimov, N. M., & Shakhanova, S. S. (2023). Prostate cancer morbidity and mortality among men in high-risk areas. Eurasian Medical Research Periodical, 18, 101–104.
