ASSESSMENT OF CARDIORENAL SYNDROME IN CHILDREN WITH ACUTE NEPHRITIC SYNDROME
Keywords:
Acute nephritic syndrome, cardiorenal syndrome, cardiometria, heart hemodinamic, childrenAbstract
Objective is to develop methods for early diagnosis, prognosis of cardiorenal syndrome in children with acute nephritic syndrome.
Materials and Methods: The study was conducted on 105 children hospitalized with acute nephritic syndrome in the nephrology department of the Samarkand Regional Children's Multidisciplinary Medical Center.
The study used general clinical, laboratory (hematological, biochemical), instrumental and statistical methods of research.
Results: For the first time, the frequency of 64.8% of cardiorenal syndrome, and specific clinical symptoms (weakness, fatigue, arterial hypertension, systolic murmur, arrhythmias and chest pain) in children with acute nephritic syndrome were determined. Substantiated the diagnostic value of the cardiometric method (sensitivity 97.1%, diagnostic accuracy 95.2%, specificity 91.9%) in the diagnosis of cardiovascular diseases in children with acute nephritic syndrome.
Conclusions. As a result of cardiometric studies in patients with acute nephritic syndrome, it was found that cardiorenal syndrome is manifested by significant changes in hemodynamic parameters.
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Статья поступила в редакцию 03.03.2024; одобрена после рецензирования 20.04.2024; принята к публикации 26.04.2024.
The article was submitted 03.03.2024; approved after reviewing 20.04.2024; accepted for publication 26.04.2024.
Информация об авторах:
Юлдашев Ботир Ахматович к.м.н., доцент, Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: botir1969@mail.ru.uz, 0000-0003-2442-1523
Муродова Малика Джамоловна PhD. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. E-mail: mali007@mail.ru, Orcid: 0000-0002-5861-5329
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Юлдашев Б.А. — идеологическая концепция работы, написание текста; редактирование статьи;
Муродова М.Д. — сбор и анализ источников литературы, написание текста.
Information about the authors:
Yuldashev B.A. PhD. Associate professor. Samarkand State Medical University, Samarkand, Uzbekistan Е-mail: botir1969@mail.ru.uz, Orcid: 0000-0003-2442-1523
Murodova M.D. PhD. Samarkand State Medical University, Samarkand, Uzbekistan. E-mail: mali007@mail.ru, Orcid: 0000-0002-5861-5329
Sources of funding: The work did not receive any specific funding.
Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.
Contribution of the authors:
Yuldashev B.A. — ideological concept of the work, writing the text; editing the article;
Murodova M.D. — collection and analysis of literature sources, writing the text.
