BRAIN REGENERATION: STEM CELL THERAPY FOR NEURODEGENERATIVE DISEASES
Keywords:
stem cells, Alzheimer's disease, Parkinson's disease, neurodegenerative diseasesAbstract
The article analyzes a literature review of publications that discuss the positive and negative points of view of the use of stem cells in brain therapy for neurodegenerative diseases. The ability of a stem cell to transform into any human cell, especially a neuron, in such formidable, progressive and incurable, but common neurodegenerative diseases as Alzheimer's disease and Parkinson's disease, as well as multiple sclerosis, is a major breakthrough in neurology. However, there are problematic dilemmas associated with the process of obtaining and using stem cells in the context of treating these diseases. The process of extracting them may use embryonic stem cells, raising serious questions about the ethics of stem cells. Some believe that manipulating these cells in the early stages of development could be seen as interfering with natural processes or ignoring potential life. Financial implications also pose significant obstacles. Developing new treatments is an expensive process with no guaranteed success or return on investment. Therefore, many investors are hesitant to invest in this area. Other challenges include scientific issues such as ensuring the safety and effectiveness of stem cell therapies. For example, there is a risk that the transplanted cells may cause tumors or trigger an immune response. Despite challenges posed by ethical considerations and funding needs, the promise of stem cell therapy illuminates the path to revolutionary solutions that could transform the lives of people suffering from devastating neurological diseases.
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Статья поступила в редакцию 05.03.2024; одобрена после рецензирования 21.04.2024; принята к публикации 26.04.2024.
The article was submitted 05.03.2024; approved after reviewing 21.04.2024; accepted for publication 26.04.2024.
Информация об авторах:
Ризаев Жасур Алимджанович- д.м.н., профессор, ректор. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: sammi@sammi.uz, https://orcid.org/0000-0001-5468-9403
Хакимова Сохиба Зиядуллоевна - DSc, доцент, заведующая кафедрой неврологии факультета последипломного образования, Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: hakimovasohiba@list.ru, https://orcid.org/0000- 0003-4804-3651
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Ризаев Ж.А. — идеологическая концепция работы, написание текста; редактирование статьи;
Хакимова С.З. — сбор и анализ источников литературы, написание текста.
Information about the authors:
Jasur A. Rizaev — DSc, professor, rector Samarkand state medical university. Samarkand, Uzbekistan; E-mail: sammi@sammi.uz, https://orcid.org/0000-0001-5468-9403
Sohiba Z. Khakimova — DSc, associate professor, Associate Professor, head of the department of neurology, Faculty of Postgraduate Education,. Samarkand state medical university. Samarkand, Uzbekistan; Е-mail: hakimovasohiba@list.ru, https://orcid.org/0000- 0003-4804-3651
Sources of funding: The work did not receive any specific funding.
Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.
Contribution of the authors:
Rizaev JA — ideological concept of the work, writing the text; editing the article;
Khakimova SZ— collection and analysis of literature sources, writing the text
