NEYRODEGENERATIV KASALLIKLARDA ILDIZ HUJAYRA TERAPIYASI - MIYA REGENERASI
##article.subject##:
ildiz hujayralar, Altsgeymer kasalligi, Parkinson kasalligi, neyrodegenerativ kasalliklar##article.abstract##
Maqolada neyrodegenerativ kasalliklar uchun miya terapiyasida ildiz hujayralaridan foydalanishning ijobiy va salbiy nuqtai nazarini muhokama qiladigan nashrlarning adabiyot sharhi tahlil qilinadi. Altsgeymer kasalligi va Parkinson kasalligi, shuningdek, skleroz kabi dahshatli, progressiv va davolab bo'lmaydigan, ammo keng tarqalgan neyrodegenerativ kasalliklarda ildiz hujayraning har qanday inson hujayrasiga, ayniqsa neyronga aylanishi qobiliyati nevrologiyada katta yutuqdir. Biroq, bu kasalliklarni davolash kontekstida ildiz hujayralarini olish va ulardan foydalanish jarayoni bilan bog'liq muammoli dilemmalar mavjud. Ularni olish jarayonida embrion ildiz hujayralaridan foydalanish mumkin, bu ildiz hujayralarining etikasi haqida jiddiy savollar tug'diradi. Ba'zilarning fikricha, bu hujayralarni rivojlanishning dastlabki bosqichlarida manipulyatsiya qilish tabiiy jarayonlarga aralashish yoki potentsial hayotni e'tiborsiz qoldirish deb qaralishi mumkin. Moliyaviy oqibatlar ham katta to'siqlarni keltirib chiqaradi. Yangi davolash usullarini ishlab chiqish muvaffaqiyat yoki investitsiya daromadi kafolatlanmagan qimmat jarayondir. Shuning uchun ko'plab investorlar ushbu sohaga sarmoya kiritishga ikkilanishadi. Boshqa muammolar qatoriga ildiz hujayralarini davolashning xavfsizligi va samaradorligini ta'minlash kabi ilmiy masalalar kiradi. Misol uchun, transplantatsiya qilingan hujayralar o'smalarni keltirib chiqarishi yoki immunitet reaktsiyasini qo'zg'atishi xavfi mavjud. Axloqiy mulohazalar va moliyaviy ehtiyojlar bilan bog'liq qiyinchiliklarga qaramay, ildiz hujayra terapiyasi va'dasi halokatli nevrologik kasalliklardan aziyat chekayotgan odamlarning hayotini o'zgartirishi mumkin bo'lgan inqilobiy echimlar yo'lini yoritadi.
Библиографические ссылки
Aminov, Z. Z., Khakimova, S. Z., & Davlatov, S. S. Improvement Of Treatment Protocols Of Pain Syndrome In Patients With Chronic Brucellosis. European Journal of Molecular & Clinical Medicine. 2020;7(3): 2540-2545.
Bang O.Y., Kim E. H., Cha J.M., Moon G. J. Adult Stem Cell Therapy for Stroke: Challenges and Progress. J. Stroke. 2016;18(3):256–266.
Khakimova S., Gapparova N., Samiev A., Hamdamova B., Kodirov U., Karabaev S. Peculiarities of ENMG examinations in patients with chronic pain syndrome dorsopathies of compression-ischemic genesis. Journal of Biomedicine and Practice. 2021;6(6):80-87.
Napoli E., Lippert T., Borlongan C. V. Stem Cell Therapy: Repurposing Cell-Based Regenerative Medicine Beyond Cell Replacement.Adv. Exp. Med. Biol. 2018;174.
Zerna C., Lindsay M.P., Fang J., Swartz R.H., Smith E.E. Outcomes in Hospitalized Ischemic Stroke Patients with Dementia on Admission: A Population-Based Cohort Study. Can. J. Neurol. Sci. 2018; 45(3):290–294.
Ziyadullayevna, S. K., & Alisherovna, D. A. Results Of Examination Of Patients With Radiculopathies In Chronic Brucellosis. The American Journal of Medical Sciences and Pharmaceutical Research. 2020;2(10):37-43.
Baranov E.V., Buravskiy A.V., Kvacheva z.b., Vasilevich I.b., Tret'yak s.I., Volotovskiy I.D. Local transplantation of mul'tipotentnykh of mezenkhimal'nykh barrel cages of fatty fabric and fibroblastov of skin: features of regeneration of a skin cover and comparative estimation of indexes of cicatrization of experimental ranevykh defects. Military medicine. 2017;43(2):79–86.
Kulikovskaya of V. And., Gilevskaya k.s., Pinchuk s.v., Kraskovskiy A.N., Vasilevich I.b., Matievskiy to To. And., Agabekov V.E., Volotovskiy I. D. Biopolimernye mul'tisloynye tapes as transmitters of me- zenkhimal'nykh of barrel cages. Lectures of the National academy of sciences of Byelorussia. 2017;61(3):38–46
Isakulov , sh. R., Rizaev , f. A. (2022). Craniofacial zharohatlarda tibby yordamni tashkillashtirishni takimillashtirish va davolash usullarini yakhshilashga zamonaviy Jondaszow . Journal of Biomedicine and Practice, 7(1). 2022. – T. 7. – No. 1.
Jasur Alimdjanovich Rizaev , Nodirjon Kadyrovich Khaidarov , & Sharif Yuldashevich Abdullaev . (2021). CURRENT APPROACH TO THE DIAGNOSIS AND TREATMENT OF GLOSSALGIA (LITERATURE REVIEW). World Bulletin of Public Health, 4, 96-98. Retrieved from https://scholarexpress.net/index.php/wbph/article/view/283
Статья поступила в редакцию 05.03.2024; одобрена после рецензирования 21.04.2024; принята к публикации 26.04.2024.
The article was submitted 05.03.2024; approved after reviewing 21.04.2024; accepted for publication 26.04.2024.
Информация об авторах:
Ризаев Жасур Алимджанович- д.м.н., профессор, ректор. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: sammi@sammi.uz, https://orcid.org/0000-0001-5468-9403
Хакимова Сохиба Зиядуллоевна - DSc, доцент, заведующая кафедрой неврологии факультета последипломного образования, Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: hakimovasohiba@list.ru, https://orcid.org/0000- 0003-4804-3651
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Ризаев Ж.А. — идеологическая концепция работы, написание текста; редактирование статьи;
Хакимова С.З. — сбор и анализ источников литературы, написание текста.
Information about the authors:
Jasur A. Rizaev — DSc, professor, rector Samarkand state medical university. Samarkand, Uzbekistan; E-mail: sammi@sammi.uz, https://orcid.org/0000-0001-5468-9403
Sohiba Z. Khakimova — DSc, associate professor, Associate Professor, head of the department of neurology, Faculty of Postgraduate Education,. Samarkand state medical university. Samarkand, Uzbekistan; Е-mail: hakimovasohiba@list.ru, https://orcid.org/0000- 0003-4804-3651
Sources of funding: The work did not receive any specific funding.
Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.
Contribution of the authors:
Rizaev JA — ideological concept of the work, writing the text; editing the article;
Khakimova SZ— collection and analysis of literature sources, writing the text
