RESULTS OF TRIMODAL THERAPY FOR INVASIVE BLADDER CANCER

Authors

  • BOYKO Elena Vladimirovna
  • TUYCHIEV Anvar Pardaboyevich

Keywords:

bladder cancer, relapse, trimodal therapy

Abstract

Bladder cancer most of these tumors are represented by urothelial cancer and can be characterized by varying degrees of differentiation and invasiveness. In many cases, Bladder cancer develops against the background of generalized metaplasia of the entire urothelium from the renal pelvis to the urethra. This explains the tendency for multiple tumors to appear and Bladder cancer to recur after resection. Urothelial cancer cells can also migrate and implant into other areas of the urothelium, which makes it difficult to determine the causes of a re-detected tumor: incomplete removal of the primary, migration and implantation of cancer cells, multiple tumors or a different combination of them.

References

Гладков О. А., Зуков Р.А., Матвеев В. Б. и др. Практические рекомендации по лекарственному лечению рака мочевого пузыря // Злокачественные опухоли: практические рекомендации RUSSCO. – 2021. – Т. 11, № 32: DOI: 10.18027 / 2224 5057 2021 11 3s2-32.

Джойнер М.С., ван дер Когель О.Д. Основы клинической радиобиологии (гл. 18. Совместное применение лучевой и химиотерапии); пер. с англ. – М.: БИНОМ. Лаборатория знаний, 2013. – 600 с. 3.

Каприн А. Д., Старинский В. В., Шахзадова А. О. Злокачественные новообразования в России в 2019 году (заболеваемость и смертность) − Москва: МНИОИ им. П.А. Герцена − филиал ФГБУ «НМИЦ радиологии» Минздрава России. − 2020. − 252 с. 4. Клинические рекомендации. Рак мочевого пузыря. – 2020.

Новиков А.И., Леоненков Р.В., Темкин Д.Б. и др. Трансуретральная резекция карциномы мочевого пузыря, распространяющейся на устье мочеточника // Онкоурология. – 2021. – Т. 17, № 2. – С. 104-11.

Ajib K., Tjong M.C., Tan G.H. et al. Canadian experience of neoadjuvant chemotherapy on bladder recurrences in patients managed with trimodal therapy for muscle-invasive bladder cancer // Can Urol Assoc J. – 2020. – Vol. 14, N 12. – P. 404-410.

Arcangeli G., Arcangeli S., Strigari L. A systematic review and meta-analysis of clinical trials of bladder-sparing trimodality treatment for muscle-invasive bladder cancer (MIBC) // Crit Rev Oncol Hematol. – 2015. – Vol. 94, N 1. – P. 105-15.

Babjuk M., Burger M., Capoun O. et al. European association of urology guidelines on non-muscle-invasive bladder cancer (Ta, T1, and carcinoma in situ) // Eur Urol. – 2021. – Vol. 9: S0302-2838(21) 01978-3.

Bertz S., Wach S., Taubert H. et al. Micropapillary morphology is an indicator of poor prognosis in patients with urothelial carcinoma treated with transurethral resection and radiochemotherapy // Virchows Arch. – 2016. – Vol. 469, N 3. – P. 339-44.

Bladder cancer: diagnosis and management of bladder cancer: © NICE (2015) Bladder cancer: diagnosis and management of bladder cancer

Published

2024-12-25