VALUE OF CARDIAC MARKERS IN SICK CHILDREN COMMUNITY AQUIRED PNEUMONIA WITH MYOCARDITIS
Keywords:
myocarditis, children, cardiac troponins I, pneumonia, heart failureAbstract
Currently, in cardiology, it is important to determine troponins as a biochemical marker of cardiomyocyte necrosis. The aim of this work was to identify markers of myocardial damage and identify the most significant of them in children with pneumonia. On the basis of the SF RSCEMA, 150 patients aged from 6 months to 7 years old were examined. The parameters of troponin I, α-HBDG, MVKK were determined. The parameters of troponin I, α-HBDG, MVKK were determined. The exclusion criteria were congenital heart defects (CHD), cardiac arrhythmias, genetic anomalies, chronic bronchopulmonary diseases, if changes in troponins in the blood were observed. This is due to the absence of episodes of acute hypoxia and death of cardiomyocytes. The results of the study showed that studies of clinical symptoms, echocardiography, hemostasis and cardiac markers indicate the peculiarities of the course of community-acquired pneumonia with myocarditis in children and need further confirmation, including analysis of the correlation relationships between them.
References
Amelyushkina V.A., Kotkina T.I., Titov V.N. Troponin: structure, properties and mechanism of functioning. chemical markers of the affected myocardium. Wedge. and lab. Biochemistry. 1999; 64(9): 1155–1174
Galysheva N.V. Optimization of approaches to the diagnosis of heart pathology in newborns”: Abstract of the thesis. diss. … cand. honey. Sciences. Yekaterinburg, 2009
Slobin P.I. Clinical and biochemical features of the adaptation of cardiac activity in congenital heart defects in newborns: Abstract of the thesis. diss. cand. honey. Sciences. Astrakhan, 2000
Filatov V.L., Katrukha A.G., Bulargina T.V., Gusev N.B. Bio diagnostics. 1999; 7:25–32
Chaulin A. M., Duplyakov D. V. An increase in cardiac troponins not associated with acute coronary syndrome. Part 1-2 //Cardiology: News. Opinions. Education. – 2019. – no. 2 (21)
Shibaev A.N. The value of clinical and functional methods of research and determination of serum troponin T in the diagnosis and rationale for the treatment of cardiovascular disorders in newborns who have undergone perinatal hypoxia: Abstract of the thesis. diss. cand. honey. Sciences, Tver, 2004.
Shmatkova Yu.V. Clinical significance of the dynamics of the content of troponin I, myoglobin and cytokines in chronic heart failure in children: Abstract of the thesis. diss. honey. Sciences. M., 2006.
Apple FS, Christenson RH, Valdes RJ. Simultaneous rapid GEOTAR-Media, 2008. measurement of whole blood myoglobin, creatine cinase MB, and cardiac troponin I by the triage cardiac panel for detection of myocardial infarction. Clin. Chem. 1999; (45): 199–205
Rifai N, Douglas PS, Toole MO. Cardiac troponin T and I, electrocardiographic wall motion analysis and eje. J. Cardiovasc. Pharmaco. 1985; 7(3): 424–436
Ризаев, Ж. А., Агабабян, И. Р., Ярашева, З. Х., & Мухамедова, М. Г. (2022). Значение коморбидных состояний в развитии хронической сердечной недостаточности у больных пожилого и старческого возраста. Достижения науки и образования, (1 (81)), 75-79.
