HYPERPLASTIC PROCESSES IN PREMENOPAUSAL AGE WOMEN
Keywords:
endometrial hyperplastic processes (HPE), premenopausal age, combined oral contraceptives (COCs), premenstrual syndrome (PMS), treatment methodsAbstract
Objective: to determine the relationship of hyperplastic processes with premenopausal age and their manifestations in the form of abnormal uterine bleeding.
Materials and Methods: The study was conducted on 50 premenopausal patients with a history of hyperplastic processes who were treated in the gynecological department of the first multidisciplinary clinic of Samarkand State Medical University during 2022. The study used general clinical, laboratory (hematological, biochemical, immunological), instrumental and statistical research methods.
Results: The main complaints at the time of admission to the hospital were profuse vaginal bleeding and pain, and in 20 women (40%) bleeding was irregular, prolonged, scanty, almost all patients complained of weakness, fatigue and irritability. In the general analysis of blood, anemia was observed in all, in 20% of women the ESR increased to 20 mm / h, in the general analysis of urine, signs of inflammation were observed in 26%, in the smear - dysbacteriosis in 36% of cases. Hormonal imbalance was observed in 48% of women. It was noted that the level of hormones in all examined women was almost 1.5 times lower than in healthy women of the same age. All women were prescribed antihemorrhagic and antianemic treatment.
Conclusions. Hyperplasia of the endometrial layer of the uterus in all cases was expressed by abnormal bleeding, the phased treatment of which once again confirms the need for a full diagnosis. In premenopausal age, it can be said that this condition is associated with a violation of the hormonal background.
References
Алиева Д.А., Аскарова З.З., Каримова Г.С., Значение гистероскопии в диагностике аномальных маточных кровотечений в перименопаузе-Вопросы науки и образования. 2020.-20-26с
Аскарова З.З. Частота патоморфологических изменений эндо-и миометрия в развитие аномальных маточных кровотечений у женщин в перименопаузе- Достижение науки и образования,2020.-113-116с.
Габидуллина Р. И. и др. Гиперпластические процессы эндометрия: современная тактика ведения пациенток //Consilium Medicum. – 2019. – Т. 21. – №. 6. – С. 53-58.
Кузнецова И. В. Гиперпластические процессы эндометрия //Вопросы гинекологии, акушерства и перинатологии. – 2007. – Т. 6. – №. 5. – С. 68-77.
Кенжебай Э. А., Ким М. С., Азизова Э. Д. Современная диагностика и лечение аномальных маточных кровотечений //Евразийское Научное Объединение. – 2021. – №. 5-2. – С. 98-100.
Курбаниязова В. Э., Ахтамова Н. А., Хамидова Ш. М. Интенсивное восстановление женщин репродуктивного возраста перенесших операцию Кесарево сечение //Проблемы биологии и медицины. – 2019. – №. 4. – С. 53-55.
Романова И. С., Косик Д. Ю. ТАКТИКА ВЕДЕНИЯ ПАЦИЕНТОК С АНОМАЛЬНЫМИ МАТОЧНЫМИ КРОВОТЕЧЕНИЯМИ //Редакційна колегія. – С. 169.
Тоджиева Н. И., Худоярова Д. Р., Базарова З. З. Совершенствование методов лечения гиперпластических процессов эндометрия в пременопаузе //Профессионал года. – 2018. – Т. 2018. – С. 81-84.
Тоджиева Н. И. premenopauzal davrdagi endometriyning giperplastik jarayonlari: davolash usullarini takomillashtirish //журнал биомедицины и практики. – 2022. – т. 7. – №. 5.
Чернышенко Т. А. и др. Возможности внутриматочной хирургии в лечении больных с аномальными маточными кровотечениями в пременопаузальном периоде //Кремлевская медицина. Клинический вестник. – 2017. – №. 4-2. – С. 26-33.
Хушвахтова Э. Х. Гиперпластические процессы эндои миометрия у женщин различных возрастных групп //Доклады Академии наук Республики Таджикистан. – 2009. – Т. 52. – №. 1. – С. 64-69.
Хомидова Ш. М. Уровень антимюллерова гормона у женщин с преждевременным истощением яичников //Достижения науки и образования. – 2020. – №. 3 (57). – С. 104- 107.
ХАСАНОВА Д. А. АУТОИММУННЫЙ ТИРЕОИДИТ: БЕРЕМЕННОСТЬ И РОДЫ //ЖУРНАЛ БИОМЕДИЦИНЫ И ПРАКТИКИ. – 2022. – Т. 7. – №. 5.
Askarova Z. Z. et al. Value of hysteroscopy and genetic research of women with abnormal uterine bleeding in perimenopause //Eur J Mol Clin Med. – 2021. – Т. 8. – №. 1. – С. 409-416.
Ахтамова О. Ф. ANTIPHOSPHOLIPID SYNDROME AND MISCARRIAGE //УЗБЕКСКИЙ МЕДИЦИНСКИЙ ЖУРНАЛ. – 2022. – Т. 3. – №. 4.
Doniyorovna K. D. et al. AUTOIMMUNE THYROIDITIS AND IODINE DEFICIENCY //ResearchJet Journal of Analysis and Inventions. – 2022. – Т. 3. – №. 7. – С. 1-6.
Davis E., Sparzak P. B. Abnormal uterine bleeding. – 2018.
Iskandarovna T. N., Rakhimovna K. D. Risk factors for the development of endometrial hyperplastic processes in premenopause //Биомедицина ва амалиёт журнали. – с. 72.
Fozilovna A. O., Raximovna X. D. ANTIPHOSPHOLIPIID SYNDROME AND MISSION OF PREGNANCY //UMUMINSONIY VА MILLIY QАDRIYATLАR: TIL, TА’LIM VА MАDАNIYAT. – 2022. – Т. 1. – С. 13-15.
Khasanova D. PREMENSTRUAL SYNDROME IN THE MODERN SCIENCE //International Bulletin of Medical Sciences and Clinical Research. – 2022. – Т. 2. – №. 12. – С. 16-22.
Khudoyarova, D. R. Improvement of methods of natural fertility restoration in women with infertility caused by endometriosis / D. R. Khudoyarova, Z. A. Kobilova, S. A. Shopulotov // Здоровье, демография, экология финно-угорских народов. – 2020. – No 4. – P. 53-55. – EDN YGGDOO.
Khudoyarova Dildora Rakhimovna, & Shopulotova Zarina Abdumuminovna. (2022). VACUUM - EXTRACTION OF THE FETUS BY DIFFERENT METHODS. Academicia Globe: Inderscience Research, 3(06), 238–240. https://doi.org/10.17605/OSF.IO/A3MS9
Khafaga A., Goldstein S. R. Abnormal uterine bleeding //Obstetrics and Gynecology Clinics. – 2019. – Т. 46. – №. 4. – С. 595-605.
Khudoyarova D. S. D. R., Tilavova S. A., Shopulotova Z. A. MANIFESTATIONS OF EXAMINATION OF CHRONIC PYELONEPHRITIS IN PREGNANT WOMEN (CLINICAL CASE) //Thematics Journal of Microbiology. – 2022. – Т. 6. – №. 1.
Pulatov U., Hamdullaev M. LUS THERAPY IN PREGNANT WOMEN WITH CHRONIC RHINOSINUSITIS //Zamonaviy dunyoda tabiiy fanlar: Nazariy va amaliy izlanishlar. – 2022. – Т. 1. – №. 18. – С. 37-40.
Jasur Rizayev Alimjanovich, Larisa Rubenovna Agababyan, Anvar Ibragimovich Kamalov. AYOLLARDA TUG‘RUQDAN KEYINGI QON KETISHLARNI OLDINI OLISH VA ULARGA QARSHI KURASHISH BO‘YICHA KO‘RSATILAYOTGAN XIZMATLAR SIFATINING MONITORINGINI TASHKIL ETISH// Oriental Renaissance: Innovative, educational, natural and social sciences Volume 1_ ISSUE 10, 2021 p. 166-169
Alimjanovich J. R., Agababyan L. R., Kamalov A. I. Prevention and Treatment of Postpartum Hemorrhage //CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. – 2021. – Т. 2. – №. 4. – С. 204-209
Rakhimovna K. D., Abdumuminovna S. Z. The role of staphylococcal infection in the structure of inflammatory diseases //Web of Scientist: International Scientific Research Journal. – 2022. – Т. 3. – №. 6. – С. 1180-1183.
Rakhimovna K. D., Abdumuminovna S. Z. Vacuum-extraction of the fetus by different methods //Academicia Globe: Inderscience Research. – 2022. – Т. 3. – №. 06. – С. 238-240.
TODJIEVA N. I., ugli SHOPULOTOV S. A. COMMUNICATION OF PRE-CLAMPSIA OF SEVERE DEGREE AND EXTROGENITAL DISEASES //БИОМЕДИЦИНА ВА АМАЛИЁТ ЖУРНАЛИ. – С. 77.
Shakhanova S. et al. MELANOMA OF THE SKIN AND PREGNANCY //Евразийский журнал академических исследований. – 2023. – Т. 3. – №. 3. – С. 120-128.
Zafarjanovna K. F., Nuralievna S. N., Zafarjonovna A. Z. Features of the Morphological Structure of the Endometrium in Women of Reproductive Age with Abnormal Uterine Bleeding //Research Journal of Trauma and Disability Studies. – 2022. – Т. 1. – №. 10. – С. 258-262.
Zafarovna B. Z. et al. Quality of life of women undergoing obstetric hysterectomy //European science review. – 2018. – №. 9-10-2. – С. 38-40.
Wouk N., Helton M. Abnormal uterine bleeding in premenopausal women //American family physician. – 2019. – Т. 99. – №. 7. – С. 435-443.
