THE STATE OF THE MOUTH IN CHILDREN AND ADOLESCENTS WITH DIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA

Authors

  • SHAYMATOVA Azizakhon Rustambekovna
  • GAFFOROV Sunnatullo Amrulloevich

Keywords:

differentiated connective tissue dysplasia, carious lesions of the teeth, periodontitis, Marfan syndrome, Ehlers-Danlos syndrome, Alport syndrome, osteogenesis imperfecta, epidermolysis bullosa

Abstract

Purpose: To assess the frequency and occurrence of dental pathology in children and adolescents suffering from various forms of connective tissue dysplasia, as well as to determine their clinical features.

Methods: A complex of general clinical studies was carried out - questioning, general examination, instrumental, biochemical, chemiluminescent methods, a diagnosis of DCTD was made, with the participation of a geneticist and a rheumatologist to exclude chromosomal pathology in accordance with the classification. During an external examination, growth, physical development, physique, posture were assessed, proportionality, symmetry of the face, type of profile, and the presence of facial signs of dentoalveolar anomalies (DAA) were determined.

Results: The obtained results also confirm the presence of anomalies and deformities of the teeth and occlusion, a high prevalence of carious and non-carious lesions of the teeth and pathologies of periodontal tissues. At the same time, it should be noted that DCTD occurs mainly in childhood. This observation demonstrates distinct clinical symptoms, pathognomonic signs of one of the types of DCTD - osteogenesis imperfecta.

Conclusions: The analysis of the obtained results of the clinical and epidemiological study of children and adolescents with DCTD indicates a high prevalence of dental diseases and phenotypic signs that manifest themselves in the DAA. At the same time, the intensity of tooth decay by caries and periodontal tissue damage in the key age group of children aged 14-18 years is characterized as a high level of -21.2 ± 0.8, - 54.5 ± 0.4, respectively, with syndromes, OI (1d-group), also in the examined children with Marfan syndrome (1a-gr.), Ehlers-Danlos (1b-gr.) and EB (1d-gr.), an unsatisfactory hygienic condition of the PR is determined, which indicates a physical limitation of the possibility of caring for the PR.

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Published

2023-08-17