BLOOD INDICATIONS FOR HYPOXIC FACTOR DURING DIFFERENT PERIODS OF PREGNANCY IN RABBIT FEED WITH IRON AND ZINC ADDED TO THE DAILY DIET AND INSUFFICIENT CALORIE
Keywords:
pregnancy, dynamics, hypoxia factor, quantity, iron, zinc, timeAbstract
Iron deficiency, iron deficiency conditions and iron deficiency anemia remain a pressing problem worldwide, despite enormous advances in understanding the mechanisms of iron metabolism over the past 20 years. Absorbed and protein-bound iron belongs to the group of prosthetic enzymes, that is, it is a non-protein component covalently bound to a protein and plays a key role in the biological activity of this protein. It has been shown that the amount of the Hif-1a factor, a product of the expression of genes sensitive to hypoxia, in the peripheral blood of rabbits fed under different nutritional conditions and with the addition of iron and zinc preparations has unique dynamics and physiological dynamics. character depending on the type of nutrition, gestational age and stage of fetal development.
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Статья поступила в редакцию 05.01.2024; одобрена после рецензирования 18.02.2024; принята к публикации 20.02.2024.
The article was submitted 05.01.2024; approved after reviewing 18.02.2024; accepted for publication 20.02.2024.
Информация об авторах:
Мамадиярова Дилшода Умирзоковна - ассистент кафедры нормальной физиологии Самаркандского государственного медицинского университета, Узбекистан. mamadiyarovadilshoda566@gmail.com, https://orcid.org/0000-0001-9596-9401
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Мамадиярова Д.У. — идеологическая концепция работы, редактирование статьи; сбор и анализ источников литературы, написание текста.
Information about the authors:
Mamadiyarova Dilshoda Umirzakovna - Assistant at the Department of Normal Physiology of Samarkand State Medical University, Uzbekistan. mamadiyarovadilshoda566@gmail.com , https://orcid.org/0000-0001-9596-9401
Sources of funding: The work did not receive any specific funding.
Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.
Contribution of the authors:
Mamadiyarova D.U. — ideological concept of the work, editing the article; collection and analysis of literature sources, writing the text.
