THE IMPACT OF MINERAL AND ACID–BASE METABOLIC CORRECTION ON POSTOPERATIVE REHABILITATION IN CHILDREN WITH UROLITHIASIS
Keywords:
Pediatric urolithiasis; mineral metabolism; acid–base balance; metabolic disorders; postoperative rehabilitation; stone recurrence; urinary pHAbstract
Urolithiasis in children is strongly associated with metabolic disturbances that persist even after successful surgical removal of urinary calculi. Disorders of mineral metabolism and acid–base balance play a crucial role in stone recurrence and long-term renal damage. Modern minimally invasive surgical techniques effectively eliminate calculi; however, they do not address the underlying metabolic causes of stone formation. This study analyzes the significance of correcting mineral and acid–base metabolism disorders as a key component of post-operative rehabilitation in pediatric patients with urolithiasis. The findings emphasize that targeted metabolic correction significantly reduces recurrence risk and improves long-term clinical outcomes.
References
Sas DJ, Hulsey TC, Shatat IF, Orak JK. Increasing incidence of kidney stones in children evaluated in the emergency department. J Pediatr. 2010;157(1):132–137. doi:10.1016/j.jpeds.2010.02.004
Kirejczyk JK, Porowski T, Filonowicz R, et al. Pediatric urolithiasis: a systematic metabolic approach. Pediatr Nephrol. 2014;29(1):53–60. doi:10.1007/s00467-013-2571-9
Tekin A, Tekgul S, Atsu N, Bakkaloglu M, Kendi S. Risk factors for pediatric urolithiasis: a prospective study. Urology. 2000;56(6):1075–1079. doi:10.1016/S0090-4295(00)00793-5
Hoppe B, Kemper MJ. Diagnostic examination of the child with urolithiasis or nephrocalcinosis. Pediatr Nephrol. 2010;25(3):403–413. doi:10.1007/s00467-008-1073-x
Pak CYC. Medical prevention of renal stone disease. Nephron. 1999;81(Suppl 1):60–64. doi:10.1159/000046329
Milliner DS, Murphy ME. Urolithiasis in pediatric patients. Mayo Clin Proc. 1993;68(3):241–248. doi:10.1016/S0025-6196(12)60342-5
Türk C, Neisius A, Petrik A, et al. EAU Guidelines on Urolithiasis. Eur Urol. 2023.
Coe FL, Evan A, Worcester E. Kidney stone disease. J Clin Invest. 2005;115(10):2598–2608. doi:10.1172/JCI26662
Rizaev , Zh., Shomurodov , K., & Agzamova , S. (2022). MEDICAL REHABILITATION OF PATIENTS WITH FRACTURES OF THE ZYKYMOGO-ORBITAL COMPLEX. Journal of Dentistry and Craniofacial Research, 1(2), 8–11. https://doi.org/10.26739.2181-0966-2020-2-1
Inogamov Sh. M., Sadikov A. A., Rizaev Zh. A. METHODS FOR PREVENTION OF DAMAGE TO THE DENTAL APPARATUS AMONG ATHLETES PLAYING CONTACT SPORTS / / Biology. – 2021. – No. 1. – P. 125.
Raimkulova D.F., Rizaev Zh.A., Sadikov A.A. Assessment of endothelial dysfunction and oxidative stress in athletes of various sports // Problems of biology and medicine. – 2020. – T. 5. – No. 122. – pp. 109-112.