ЭКССУДАТИВЛИ ЎРТА ОТИТДА УЗОҚ МУДДАТЛИ АНТИБИОТИК ТЕРАПИЯСИНИНГ САМАРАДОРЛИГИ
##article.subject##:
Средний отит, экссудативный отит, антибиотикотерапия, амоксициллин, колонизация патогенов, педиатрия, доступ к медицине##article.abstract##
Ўрта отит айниқса, Марказий Осиё ва Россияда тиббий ёрдам чекланган жойларда долзарб муаммо бўлиб қолмоқда. Тадқиқот узоқ муддатли амоксициллин терапиясининг самарадорлигини плацебо билан солиштиришни мақсад қилди. Самарқанд Давлат Тиббиёт Университетида ўтказилган тадқиқотда 12 ойдан кичик 100 бола иштирок этди. Тимпанометрия асосида ўрта қулоқ ҳавоси тикланиши асосий натижа сифатида баҳоланди. Натижалар амоксициллин гуруҳида камроқ перфорация ва юқори даволаш самарадорлигини кўрсатди. Антибиотик гуруҳида патоген ташуви камайган. Бу терапия тиббий ёрдам чекланган жойларда хавфли болаларга фойда келтириши мумкин.
Библиографические ссылки
Mahadevan M, Navarro-Locsin G, Tan HK, Yamanaka N, Sonsuwan N, Wang PC, Dung NT, Restuti RD, Hashim SS, Vijayasekaran S. A review of the burden of disease due to otitis media in the Asia-Pacific. International Journal of Pediatric Otorhinolaryngology. 2012 May 1;76(5):623-35.
Ren Y, Sethi RK, Stankovic KM. Acute otitis media and associated complications in United States emergency departments. Otology & Neurotology. 2018 Sep 1;39(8):1005-11.
Atkinson H, Wallis S, Coatesworth AP. Acute otitis media. Postgraduate medicine. 2015 Jul 4;127(4):386-90.
Mayanskiy N, Alyabieva N, Ponomarenko O, Pakhomov A, Kulichenko T, Ivanenko A, Lazareva M, Lazareva A, Katosova L, Namazova-Baranova L, Baranov A. Bacterial etiology of acute otitis media and characterization of pneumococcal serotypes and genotypes among children in Moscow, Russia. The Pediatric infectious disease journal. 2015 Mar 1;34(3):255-60.
Tamir SO, Shemesh S, Oron Y, Marom T. Acute otitis media guidelines in selected developed and developing countries: uniformity and diversity. Archives of Disease in Childhood. 2017 May 1;102(5):450-7.
DeAntonio R, Yarzabal JP, Cruz JP, Schmidt JE, Kleijnen J. Epidemiology of otitis media in children from developing countries: A systematic review. International Journal of Pediatric Otorhinolaryngology. 2016 Jun 1;85:65-74.
Kosyakov SI, Minavnina JV, Phillips JS, Yung MW. International recognition of the chronic otitis media questionnaire 12. The Journal of Laryngology & Otology. 2017 Jun;131(6):514-7.
Phillips JS, Yung MW, Nunney I, Doruk C, Kara H, Kong T, Quaranta N, Peñaranda A, Bernardeschi D, Dai C, Kania R. Multinational appraisal of the chronic otitis media questionnaire 12 (COMQ-12). Otology & Neurotology. 2021 Jan 1;42(1):e45-9.
Korona-Glowniak I, Wisniewska A, Juda M, Kielbik K, Niedzielska G, Malm A. Bacterial aetiology of chronic otitis media with effusion in children-risk factors. Journal of Otolaryngology-Head & Neck Surgery. 2020 Jan;49(1):24.
Vishwanath S, Mukhopadhyay C, Prakash R, Pillai S, Pujary K, Pujary P. Chronic suppurative otitis media: Optimizing initial antibiotic therapy in a tertiary care setup. Indian Journal of Otolaryngology and Head & Neck Surgery. 2012 Sep;64:285-9.
Frost HM, Bizune D, Gerber JS, Hersh AL, Hicks LA, Tsay SV. Amoxicillin versus other antibiotic agents for the treatment of acute otitis media in children. The Journal of pediatrics. 2022 Dec 1;251:98-104.
