POSTXOLETSISTEKTOMIYA SINDROMINING KLINIK TAHLILI
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postxoletsistektomik sindrom, xoletsistokinin, xoletsistektomiya.##article.abstract##
Tadqiqot O’TK tufayli xoletsistektomiya qilingan 464 bemorning so'rovidan olingan ma'lumotlar asosida o'tkazildi. PXES klinik tasnifini ishlab chiqish va ushbu bemorlarni tekshirish algoritmini yaratish maqsadida 2018-2023-yillarda Samarqand davlat tibbiyot universitetining ko‘p tarmoqli klinikasida statsionar davolangan 388 nafar bemorning klinik, laboratoriya va instrumental tekshiruvlari natijalari tahlil qilindi, tasodifiy tanlab olish yo'li bilan tanlangan "Postxoletsistektomiya sindromi" tashxisi qo'yilgan.
Ushbu ish laparoskopik xoletsistektomiyaning operatsiyadan keyingi oqibatlari bilan bog'liq bo'lgan postxoletsistektomiya sindromini (PXES) keng qamrovli o'rganishni anglatadi. Ish PXES ning klinik variantlarini, jumladan dispeptik, og'riqli, ikterik, asemptomatik va Sharko variantini tahlil qiladi. Qon zardobidagi xoletsistokinin kontsentratsiyasidan foydalangan holda o't yo'llarining funktsional va strukturaviy buzilishlarini differentsial tashxislashga alohida e'tibor beriladi. Tadqiqotda, shuningdek, safroning litogenik xususiyatlarining ahamiyati, gumoral tartibga solishdagi o'zgarishlar va PXES shakllanishidagi ekzokrin jigar buzilishlari muhokama qilinadi. Ishda xoletsistektomiyadan so'ng bemorlarda o't yo'llari yetishmovchiligini klinik kuzatish va tuzatish zarurligiga urg'u beriladi.
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