БОЛАЛАРДА НЕФРОБЛАСТОМАНИ ВИЗУАЛИЗАЦИЯ ҚИЛИШНИНГ ЗАМОНАВИЙ КРИТЕРИЙЛАРИ: МУРАККАБ РАДИОЛОГИК ЁНДАШУВ
##article.subject##:
нефробластома, Вилмс ўсмаси, болалар, УТТ, КТ, МРТ, визуализатсия, SIOP, COG, радиология##article.abstract##
Нефробластома (Вилмс ўсмаси) болаларда энг кўп учрайдиган хавфли буйрак ўсмаси бўлиб, болаларда учрайдиган барча буйрак ўсмаларининг 90 фоизини ташкил этади. Замонавий диагностика ультратовуш, компьютер ва магнит-резонанс томографиядан комплекс фойдаланишга асосланган бўлиб, бу ўсма локализацияси, ўлчамлари, қон томир инвазияси, метастазлар мавжудлиги, хавф даражаси ва босқичини халқаро SIOP ва COG, протоколлари бўйича аниқ белгилаш имконини беради. Ишда болаларда нефробластома визуализатсиясининг замонавий мезонлари, ўзига хос ультратовуш ва томографик белгилар, ўсманинг тарқалишини аниқлашда КТ ва МРТнинг роли, пастки ковак венада тромб ҳосил бўлиши, ўпка ва жигарнинг метастатик шикастланишини аниқлаш кўриб чиқилган. Жарроҳлик тактикасини танлаш ва операциядан олдинги кимётерапияга жавобни баҳолаш учун радиологик усулларнинг аҳамияти таҳлил қилинади. Комплекс радиологик ёндашув ўсмани эрта аниқлаш, аниқ босқичлаш ва даволаш самарадорлигини оширишни таъминлайди.
Библиографические ссылки
SIOP Renal Tumour Study Group. International Society of Paediatric Oncology (SIOP) Protocol for Wilms Tumour. 2023 Update.
Children’s Oncology Group (COG). Renal Tumors Committee Guidelines for Wilms Tumor Management. 2024.
Dome J.S., Fernandez C.V., Mullen E. et al. Wilms Tumor: Biology, Diagnosis, and Current Therapy. Lancet Oncology. 2021;22(12):e537–e548.
Vujanić G.M., Sandstedt B., Kelsey A. et al. Morphological and molecular basis of Wilms
tumour. Nature Reviews Urology. 2022;19(1):41–54.
Anigilaje E.A., Olutoye O.O. Imaging of Wilms Tumor: An Updated Review. Pediatric Radiology. 2022;52(5):812–826.
McDonald K., Servaes S., Frazier A.L. Imaging evaluation of pediatric renal tumors. Radiographics. 2020;40(7):1950–1966.
Smets A.M., Vujanić G.M., Wesseling J. et al. Imaging in Wilms tumour: state of the art.
European Journal of Radiology. 2023;162:110781.
Davidoff A.M. Wilms tumor. Current Opinion in Pediatrics. 2020;32(3):340–347.
Hamilton T.E., Ritchey M.L., Peterson S.M. et al. The role of preoperative imaging in Wilms tumor staging. Journal of Pediatric Surgery. 2021;56(4):736–742.
Lowe L.H., Isuani B.H., Heller R.M. et al. Pediatric renal masses: Wilms tumor and beyond. Radiologic Clinics of North America. 2020;58(5):989–1006.
Metzger M.L., Dome J.S. Current therapy for Wilms tumor. Oncology (Williston Park). 2021;35(2):71–88.
WHO Classification of Tumours Editorial Board. WHO Classification of Paediatric Tumours. 5th Edition. IARC Press; 2022.
Ching C.B., Hultman C.S., Geller J.I. Advances in the management of Wilms tumor: a 2023 review. Pediatric Blood & Cancer. 2023;70(2):e29987.
Ehrlich P.F. Wilms tumor: diagnosis and management. Seminars in Pediatric Surgery. 2022;31(3):151180.
SIOP and COG Collaborative Review. Comparison of Wilms Tumor Treatment Protocols: A Global Perspective. Journal of Pediatric Hematology/Oncology. 2020;42(8):e635–e642.
Yunusova, L., Aoyama, T., Amanullayev, R., Rizaev, J., Ikramov, G., Sakamoto, J., ... & Mamarajabov, S. (2021). Sonography and magnetic resonance tomography in monitoring of recurrent cysts lesions of the neck. Annals of Cancer Research and Therapy, 29(2), 131-134.
Yunusova, L., Rizaev, J., Aoyama, T., Mamarajabov, S., Djahangirova, D., Sakomoto, Y., & Olimjonov, K. (2021). Magnetic resonance imaging in the diagnosis of cystic lesions of the neck. Ann. Cancer Res. Ther, 29(1), 109-116.
Nodir RM, Shaxnoza SS, Farhod R. Development of new approaches in the treatment of metastatic renal cell carcinoma //Journal of research in health science. – 2020. – T. 5. – no. 4. – pp. 82-95.
