REVMATOID ARTRIT BILAN KASALLANGAN BEMORLARDA YURAK ISHEMIK KASALLIGINI XAVF OMILLARI VA KECHISHINING O’ZIGA XOS XUSUSIYATLARI

##article.authors##

  • Tairova Zarangis Kamolidinovna
  • Shodikulova Gulandom Zikriyaevna

##article.subject##:

yurak ishemik kasalligi, xavf omillari, autoimmun yallig'lanish

##article.abstract##

Maqsad: Revmatoid artrit bilan kasallangan bemorlarda yurak ishemik kasalligini xavf omillari va kechishining o’ziga xos xususiyatlarini o'rganish.

Material va metodlar: Samarqand shahar tibbiyot birlashmasining kardiorevmatologiya bo'limida 2020-2022 yillarda davolangan 84 nafar bemor tekshiruvdan o'tkazildi.

Natijalar: Yurak ishemik kasalligi (YuIK) tashxisi 32 ta (38%) bemorda qo’yilgan: ular orasida 4 (12,5%) nafarida kasallik RA kasalligi rivojlanishidan oldin, 15 (46,8%) kishida stabil zo’riqish stenokardiyasi, 7 (25,4%) bemorda-yurakning og'riqsiz ishemiyasi va 9 (28,2%) nafarida- yurakning ritm buzilishlari aniqlandi. 2 (6,25%) bemor anamnezida miokard infarkti o'tkazgan.

Xulosa. Tadqiqotga ko'ra, RA bilan og'rigan bemorlarning 38%da YuIK tashxisi qo’yilgan. 30% bemorlarda aritmiyalar va yurakning og'riqsiz ishemiyasi qayd etilgan, bu holat nosteroid yallig’lanishga qarshi dorilarni doimiy qabul qilish bilan bog'liq bo'lishi mumkin.

Библиографические ссылки

Avina-Zubieta J. A., Thomas J., Sadatsafavi M., Sadatsafavi M., Lehman A. J., Lacaille D. Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis, 2012, vol. 71, no. 9, pp. 1524-1529. doi:10.1136/annrheumdis-2011-200726.

Agca R., Heslinga S. C., Rollefstad S., Heslinga M., McInnes I. B., Peters M. J., Kvien T. K., Dougados M., Radner H., Atzeni F., Primdahl J., Södergren A., Wallberg Jonsson S., van Rompay J., Zabalan C., Pedersen T. R., Jacobsson L., de Vlam K., Gonzalez-Gay M. A., Semb A. G., Kitas G. D., Smulders Y. M., Szekanecz Z., Sattar N., Symmons D. P., Nurmohamed M. T. EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update. Ann Rheum Dis, 2017, vol. 76, no. 1, pp. 17-28. doi:10.1136/annrheumdis-2016-209775.

Bernardes M., Vieira T. S., Martins M. J., Lucas R., Costa L., Pereira J. G., Ventura F., Martins E. Myocardial Perfusion in Rheumatoid Arthritis Patients: Associations with Traditional Risk Factors and Novel Biomarkers [electronic resource]. Biomed Res Int, 2017. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434312/ (accessed 25.09.2021).

Błyszczuk P., Szekanecz Z. Pathogenesis of ischaemic and non-ischaemic heart diseases in rheumatoid arthritis. RMD Open, 2020, vol. 6, no. 1, pp. e001032. doi: 10.1136/rmdopen-2019-001032.

DeMizio D. J., Geraldino-Pardilla L. B. Autoimmunity and Inflammation Link to Cardiovascular Disease Risk in Rheumatoid Arthritis. Rheumatol Ther, 2020, vol. 7, no. 1, pp. 19-33. doi: 10.1007/s40744-019-00189-0

Lacaille D., Avina-Zubieta J. A., Sayre E. C., Abrahamowicz M. Improvement in 5-year mortality in incident rheumatoid arthritis compared with the general population-closing the mortality gap. Ann Rheum Dis, 2017, vol. 76, no. 6, pp. 1057-1063. doi:10.1136/annrheumdis-2016-209562.

Lai C. H., Hsieh C. Y., Barnado A., Huang L. C., Chen S. C., Tsai L. M., Shyr Y., Li C. Y. Outcomes of acute cardiovascular events in rheumatoid arthritis and systemic lupus erythematosus: a population-based study. Rheumatology (Oxford), 2020, vol. 59, no. 6, pp. 1355-1363. doi: 10.1093/rheumatology/kez456.

Mal K., Kumar R., Mansoor F., Kaur N., Kumar A., Memon S., Rizwan A. Risk of Major Adverse Cardiovascular Events in Patients With Rheumatoid Arthritis. Cureus, 2020, vol. 12, no. 12, pp. e12246. doi: 10.7759/cureus.12246.

Provan S. A., Lillegraven S., Sexton J., Angel K., Austad C., Haavardsholm E. A., Kvien T. K., Uhlig T. Trends in all-cause and cardiovascular mortality in patients with incident rheumatoid arthritis: a 20-year follow-up matched case-cohort study. Rheumatology, 2020, vol. 59, no. 3, pp. 505–512. doi:10.1093/rheumatology/kez371.

Shodikulova G.Z., Tairova Z.K., Khasanov O.G. ASSESSMENT OF THE STATE OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH RHEUMATOID ARTHRITIS. Journal of TMA Bulletin, 2022, issue 2, pp. 183-185.

Shodikulova G.Z. Shonazarova N.X FEATURES OF THYROID DISEASE IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH CARDIOMETABOLIC SYNDROME. Journal of cardiorespiratory research. 2022, vol 3, issue 2, pp. 22-25.

Wang H., Li X., Gong G. Cardiovascular outcomes in patients with co-existing coronary artery disease and rheumatoid arthritis. Medicine (Baltimore), 2020, vol. 99, no. 14, pp. e19658. doi: 10.1097/MD.0000000000019658.

Загрузки

##submissions.published##

2023-02-07