ЗАВИСИМОСТЬ УРОВНЯ НЕЙТРОФИЛОВ ОТ СОСТОЯНИЯ ПАРОДОНТА У БОЛЬНЫХ ХРОНИЧЕСКОЙ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА. (ЛИТЕРАТУРНЫЙ ОБЗОР)
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Aterosklerotik yurak-qon tomir kasalliklari, paradontit, neytrofillar, yallig'lanishga qarshi sitokinlar, giperurikemiya##article.abstract##
Yurak-qon tomir kasalliklarining asosiy sababi aterosklerozdir. Ateroskleroz - surunkali yallig'lanishli tomir kasalligi bo'lib, arterial devorda lipid plitalarining cho'kishiga olib keladi. Ushbu plitalarning to'planishi va rivojlanishi qon oqimini kamaytirishi mumkin, bu esa barcha organlar va to'qimalarning ishemiyasiga olib keladi, shuningdek, ateroskleroz bilan bog'liq bo'lgan asosiy yurak kasalliklariga miokard infarkti, o'tkir koronar sindrom, yurak yetishmovchiligi, aritmiya va kardiyomiopatiya kiradi. Dunyo bo'ylab yurak-qon tomir kasalliklari o'limning birinchi sababi va o'limning asosiy sababidir. Ateroskleroz surunkali yallig'lanish kasalligi bo'lganligi sababli, tadqiqotchilar boshqa yallig'lanish holatlari aterosklerozga hissa qo'shishi va kasallikning kechishini yomonlashtirishi mumkinligini tushunishga harakat qilishdi. Kam o'rganilgan yallig'lanish kasalliklaridan biri parodontit bo'lgan. Ba'zi tadqiqotlarga ko'ra, har xil turdagi blyashka natijasida paydo bo'lgan paradontal kasallik (shu jumladan gingivit, AQShda 30 yosh va undan katta yoshdagi kattalar aholisining 47,2 foiziga ta'sir qiladi. 65 yoshdan keyin bu ko'rsatkich 70% gacha oshadi. Og'iz bo'shlig'ini parvarish qilish odatlaridan tashqari, paradontal kasallikka hissa qo'shadigan omillar orasida ijtimoiy-iqtisodiy holat, jins va chekish kiradi. Paradontit dunyoda barcha kasalliklar orasida oltinchi o'rinda turadi. Paradontit bilan birgalikda aterosklerozli bemorlarda yallig'lanishni saqlab qolishda muhim rol o'ynaydigan neytrofillarning roli haqidagi ushbu maqola o'rganilmagan muammolarini biroz ochadi.
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