OBESITY AND COVID-19
Keywords:
SARS-CoV-2, COVID-19, obesity, overweight, body mass indexAbstract
Background. Research shows that excess weight negatively affects the development and progression of respiratory diseases. As the SARS-CoV-2 pandemic continues, it is important to understand how body mass index (BMI) affects the manifestation of coronavirus infection.
Aim. To study the effect of BMI on the severity of coronavirus infection.
Materials and methods of research. The observational, longitudinal, controlled study included 494 patients (311 women, 183 men) aged 18–92 years (mean age ±54.7 years). In accordance with the WHO BMI gradation, all patients were divided into 5 groups Computed tomography (CT) and the intensity of the systemic inflammatory response were used as clinical and laboratory indicators of the severity of COVID-19.
Results. Of the 494 patients, more than 70% were overweight (34%) or obese (36.2%). Patients with a body mass index (BMI) greater than 25 kg/m2 had a more severe course of the disease than patients with a lower BMI. This is confirmed by a stronger systemic inflammatory response, more significant changes in chest CT, and a higher risk of admission to the intensive care unit.
Conclusion: The risk of developing severe COVID-19 is significantly increased in the presence of overweight and/or obesity.
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