CLINICAL AND METABOLIC CHARACTERISTICS OF POLYCYSTIC OVARY SYNDROME AND OTHER FORMS OF OVULATORY DYSFUNCTION
Keywords:
PCOS, pituitary insufficiency, hypothalamic insufficiency, ovarian insufficiencyAbstract
Ovulatory disorders are among the most common causes of female infertility and present with diverse clinical, hormonal, and metabolic features. Understanding these differences is essential for personalized treatment strategies. Purpose of the study: To determine the prevalence and characteristics of hormonal, metabolic, and demographic parameters in patients with different forms of ovulatory dysfunction.
Materials and Methods. A cross-sectional comparative study included 4764 women with ovulatory dysfunction (hypophyseal, hypothalamic, ovarian insufficiency, and PCOS). Results. The most pronounced metabolic disturbances were found in PCOS and ovarian insufficiency groups: high BMI, HOMA-IR, dyslipidemia, and hyperprolactinemia. In contrast, hypothalamic and hypophyseal forms showed mainly hormonal imbalances. Conclusion. Different forms of ovulatory dysfunction show distinct metabolic profiles. These differences are crucial for risk assessment and therapeutic decisions.
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