ITSENKO-KUSHING SINDROMI
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Itsenko-Kushing sindromi, kortizol, prednizolon, mushak gipotaniyasi##article.abstract##
Kushing sindromi (KS yoki Itsenko-Kushing sindromi, giperkortisizm sindromi, Kushingoid) buyrak usti bezlari gormonlarining ortiqcha miqdori organizmga uzoq muddatli surunkali ta‘sir qilish natijasida yuzaga keladigan kasalliklar guruhini birlashtiradi, buning sababidan qat‘i nazar ularning qondagi darajasining oshishi. Aksariyat organlar va tizimlardagi patologik o’zgarishlarning patogenezi birinchi navbatda kortizolning ortiqcha ishlab chiqarilishiga asoslanadi. Sindrom ko’pincha sintetik glyukokortikoidlarni (GC) haddan tashqari iste‘mol qilish bilan rivojlanadi.
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