MECHANISM OF INFLUENCE OF OVERWEIGHT AND OBESITY ON KIDNEYS IN CHILDREN
Keywords:
obesity, children, kidney functionAbstract
Obesity and metabolic syndrome influence the functions of child’s body’s systems, provoke a progressive kidney damage and are development factors of chronic nephron number in reference to body mass. A long-term impact of these factors leads to glomerulosclerosis and chronic renal failure development. The detection of kidney disease. The kidney damage in case of obesity is related to the adipokine production failure, activation of the renin-angiotensin system, chronic inflammation, dyslipidemia, violation of kidney hemodynamics, reduction of early signs and biomarkers of the kidney damage at children is a necessary condition for prevention of the renal failure development.We studied impact of overweight and obesity in children and adolescents on renal tubular function and glomerular filtration rаte.
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