НЕКОТОРИЕ АСПЕКТЫ ЭТИОПАТОГЕНЕЗА НЕВРОЛОГИЧЕСКИХ ПРОЯВЛЕНИЙ ПРИ КОРОНАВИРУСНОЙ ИНФЕКЦИИ И ИЗУЧЕНИЕ ВЫРАЖЕННОСТИ И РАСПРОСТРАНЕННОСТИ НАРУШЕНИЙ ОБОНЯНИЯ И ВКУСА У ПАЦИЕНТОВ С SARS-COV-2

Авторы

  • Якубова Мархамат Миракрамовна
  • Файзиева Мунис Дилшод қизи

Ключевые слова:

COVID-19, SARS-CoV-2, новая коронавирусная инфекция, потеря обоняния и вкуса, аносмия, гипогевзия, ACE2 рецепторы

Аннотация

Новый коронавирус SARS-CoV-2 и вызываемая им болезнь COVID-19 наряду с поражением дыхательной системы иногда приводит к расстройствам со стороны нервной системы. В статье анализируется информация о этиопатогенических аспектах неврологических проявлениях COVID-19 и данные о выраженности и распространенности нарушений обоняния и вкуса у пациентов с коронавирусом. Потеря обоняния и вкуса при COVID-19, скорее всего, несут именно перцептивный характер. Ввиду активного накопления сведений о симптоматике данной нозологии, появились данные о характерных проявлениях болезни при легком и среднетяжелом течении, в частности о нарушении вкуса и обоняния. Хотя в настоящий момент недостаточно данных для определения точных механизмов возникновения аносмии и агевзии у пациентов с диагностированным COVID-19, имеются исследования, подтверждающие те или иные теории. В этой работе представлены результаты систематического обзора баз данных, посвященного нарушениям вкуса и обоняния при COVID-19.

Библиографические ссылки

Cascella M. et al. Features, evaluation and treatment coronavirus (COVID-19) // StatPearls [Internet]. StatPearls Publishing, 2020.

Kahn JS, McIntosh K. History and recent advances in coronavirus discovery. Pediatr Infect Dis J. 2005;24:S223‐S227. 10.1097/01.inf.0000188166.17324.60

Raoult D, Zumla A, Locatelli F, Ippolito G, Kroemer G. Coronavirus infections: epidemiological, clinical, and immunological features and hypotheses. Cell Stress. 2020. 10.15698/cst2020.04.216

Petersen E., Hui D., Hamer D.H. et al. Li Wenliang, a face to the frontline healthcare worker. The first doctor to notify the emergence of the SARS-CoV-2 (COVID-19), outbreak // Int. J. Infect. Dis. 2020. Vol. 93. P. 205-207.

Chan J.F., Kok K.H., Zhu Z., Chu H., To K.K., Yuan S., Yuen K.Y., Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan // Emerg. Microbes Infect. 2020. Vol. 9. P. 221-236.

Zhou P., Yang X.L, Wang X.G. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin // Nature. 2020. Vol. 579(7798). P. 270-273.

Guadarrama-Ortiz P., Choreño-Parra J. A., Sánchez-Martínez C. M., Pacheco-Sánchez F. J., Rodríguez-Nava A. I., García-Quintero G. Neurological Aspects of SARS-CoV-2 Infection: Mechanisms and Manifestations // Front Neurol. 2020; 11: 1039. Published 2020 Sep 4.

Li K, Wohlford-Lenane C, Perlman S, et al. Middle Eastrespiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4. J Infect Dis. 2016;213(5):712–722.

Netland J, Meyerholz DK, Moore S, et al. Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. J Virol. 2008;82(15):7264– 7275.

Chan JF, Chan KH, Choi GK, et al. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis. 2013;207(11):1743–1752.

Desforges M, Miletti TC, Gagnon M, et al. Activation of human monocytes after infection by human coronavirus 229E. Virus Res. 2007;130(1–2):228–240.

LiJ, Gao J, XuYP, et al. [Expression ofsevere acute respiratory syndrome coronavirus receptors, ACE2 and CD209Lin different organ derivedmicrovascular endothelial cells]. Zhonghua Yi Xue Za Zhi. 2007;87(12):833–837.

Li YC, Bai WZ, Hirano N, et al. Neurotropic virus tracing suggests a membranous-coating-mediated mechanism for transsynaptic communication. J Comp Neurol. 2013;521(1):203–212.

Mao L, Wang M, Chen S, et al. Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: A Retrospective Case Series Study. The Lancet. 2020 Mar 2. doi:10.2139/ssrn.3544840.

Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol. 2020;10.1002/jmv.25728. doi:10.1002/jmv.25728.

Butowt R, Bilinska K. SARS-CoV-2: olfaction, brain infection, and the urgent need for clinical samples allowing earlier virus detection. ACS Chem Neurosci. 2020;11(9):1200–1203. doi: 10.1021/acschemneuro.0c00172.

Qing H, Li Z, Yang Z, et al. The possibility of COVID-19 transmission from eye to the nose. Acta Ophthalmol. 2020;98(3):e388. doi: 10.1111/aos.14412.

Lechien JR, Chiesa-Estomba CM, Place S, et al.; COVID-19 Task Force of YO-IFOS. Clinical and epidemiological characteristics of 1,420 European patients with mild-to-moderate Coronavirus Disease 2019. J Intern Med. 2020;10.1111/ joim.13089. doi: 10.1111/joim.13089.

Gane SB, Kelly C, Hopkins C. Isolated sudden onset anosmia in COVID-19 infection. A novel syndrome? Rhinology. 2020;58(3):299–301. doi: 10.4193/Rhin20.114.

Lechien JR, Chiesa-Estomba CM, Place S, et al.; COVID-19 Task Force of YO-IFOS. Clinical and epidemiological characteristics of 1,420 European patients with mild-to-moderate Coronavirus Disease 2019. J Intern Med. 2020;10.1111/ joim.13089. doi: 10.1111/joim.13089

Hopkins C, Surda P, Kumar N. Presentation of new onset anosmia during the COVID-19 pandemic. Rhinology. 2020;58(3):295–298. doi: 10.4193/Rhin20.116.

Moein ST, Hashemian SM, Mansourafshar B, et al. Smell dysfunction: a biomarker for COVID-19. Int Forum Allergy Rhinol. 2020;10.1002/alr.22587. doi: 10.1002/alr.22587.

Yan CH, Faraji F, Prajapati DP, et al. Association of chemosen-sory dysfunction and Covid-19 in patients presenting with influenza-like symptoms. Int Forum Allergy Rhinol. 2020;10.1002/alr.22579. doi: 10.1002/alr.22579.

Gautier J-F, Ravussin Y. A new symptom of COVID-19: loss of taste and smell. Obesity (Silver Spring). 2020;28(5):848. doi: 10.1002/oby.22809.

Izquierdo-Dominguez A, Rojas-Lechuga MJ, Mullol J, Alobid I. Olfactory dysfunction in the COVID-19 outbreak. J Investig Allergol Clin Immunol. 2020. doi: 10.18176/jiaci.0567.

Temmel AF, Quint C, Schickinger-Fischer B, et al. Characteristics of olfactory dis-orders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg. 2002;128(6):635–641. doi: 10.1001/archotol.128.6.635.

Moein ST, Hashemian SM, Mansourafshar B, et al. Smell dysfunction: a biomarker for COVID-19. Int Forum Allergy Rhinol. 2020;10.1002/alr.22587. doi: 10.1002/alr.22587.

Yan CH, Faraji F, Prajapati DP, et al. Association of chemosen-sory dysfunction and Covid-19 in patients presenting with influenza-like symptoms. Int Forum Allergy Rhinol. 2020;10.1002/alr.22579. doi: 10.1002/alr.22579.

Obiefuna S, Donohoe C. Neuroanatomy, Nucleus Gustatory. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020.

Andorinho de Freitas Ferreira AC, Romão ТТ, Macedo YS, et al. COVID-19 and herpes zoster coinfection presenting with trigeminal neuropathy. Eur J Neurol. 2020:10.1111/ene.14361. doi: 10.1111/ene.14361.

Vaira LA, Salzano G, Deiana G, De Riu G. Anosmia and ageusia: common findings in COVID-19 patients. Laryngoscope. 2020;130(7):1787. doi: 10.1002/ lary.28692.

Vaira LA, Deiana G, Fois AG, et al. Objective evaluation of anosmia and ageusia in COVID-19 patients: Single-center experience on 72 cases. Head Neck. 2020;42(6):1252–1258. doi: 10.1002/hed.26204.

Wee LE, Chan YF, Teo NW, et al. The role of self-reported olfactory and gustatory dysfunction as a screening criterion for suspected COVID-19. Eur Arch Otorhinolaryngol. 2020;1–2. doi: 10.1007/s00405-020-05999-5.

Yan CH, Faraji F, Prajapati DP, et al. Association of chemosensory dysfunction and COVID-19 in patients presenting with influenza-like symptoms [published online ahead of print, 2020 Apr 12]. Int Forum Allergy Rhinol. 2020;10.1002/alr.22579.

Yan CH, Faraji F, Prajapati DP, et al. Association of chemosensory dysfunction and COVID-19 in patients presenting with influenza-like symptoms [published online ahead of print, 2020 Apr 12]. Int Forum Allergy Rhinol. 2020;10.1002/alr.22579.

Bagheri SH, Asghari AM, Farhadi M, et al. Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak. medRxiv 2020

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Опубликован

2021-09-30