CLINICAL AND NEUROLOGICAL FEATURES IN ALZHEIMER’S DISEASE
Keywords:
Alzheimer’s disease; vascular dementia; neuropsychological examinationAbstract
The article discusses the clinical and neurological features of AD. We examined 20 patients (12 women and 8 men) with Alzheimer’s disease, according to the NINCDS-ADRDA criteria, aged 60 to 85 years, who were included in the main group. The comparison group consisted of 28 patients (10 men and 18 women) with stage 2-3 chronic cerebral ischemia with vascular dementia aged 62 to 90 years. The severity of cognitive impairment prevails in patients with AD than in patients with vascular dementia and correlates with the indicators of neurological disorders in the subjects.
References
Zakharov V.V. Cognitive disorders in neurological practice. //Difficult patient – 2005. – Т.3. - №.5. –С.4-9.
Lobzin V.Yu., Kolmakova K.A., Emelin A.Yu. “A novel view on Alzheimer’s disease pathogenesis: modern conceptof amyloid clearance”. Military Medical Academy named after S.M. Kirov, St. Petersburg - REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY No. 2, 2018.
Piotrovskaya V.R. “Mental disorders of late age”. Textbook.
Shadrina I.V., Mamin G.V., Pugachev A.N. Dementia in Alzheimer’s disease - Chelyabinsk, 2013. - 40 p.
Shakhparonova N.V., Kadykov A.S. Neuroprotective therapy in the rehabilitation of patients with post-stroke cognitive impairment and in the prevention of dementia in chronic vascular diseases of the brain. // Nervous diseases. - Moscow, 2011. - No. 1. - pp. 23-26
Shprach V.V., Suvorova I.A. Cognitive disorders and dementia: monograph. Irkutsk: RIO IGIUVa, 2011.
Yavorskaya V.A., Bondar O.B., Mikhayelyan T.H., etc. Correction of cognitive disorders in patients with vascular cerebral disorders // International Medical Journal -2012. - No. 4. - pp. 16-24.
Alzheimer’s Association. 2010 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia. – 2010. – 6. –. 158-194.
Alzheimer’s disease prevalence rates rise to more than Five Million in the USA. - USA, 2015. – P. 42-49.
Piau A., Nourhashémi F., Hein C., Caillaud C., Vellas B. Progress in the development of new drugs in Alzheimer’s disease. J Nutr Health Aging, 2011;15(1):45-57.