HUMAN PAPILLOMA VIRUS AND ORAL MUCOSA LESIONS: INCREASED POTENTIAL OF MALIGNANT DEGENERATION
Keywords:
Human papillomaviruses, potentially malignant lesions, prevention of oral cancerAbstract
A significant association between human papillomavirus (HPV) infection and carcinoma has been highlighted oral squamous cell disease and, albeit variably, potentially malignant lesions of the oral cavity, such as leukoplakia, erythroleukoplakia erythroplakia. This article aims to describe the main features of HPV and analyze its role in the development of cancer. While the role of HPV infection in the onset of the uterine cervix is now well established, few are information on the prevalence, determinants and natural history of oral mucosal infection, and other studies are needed to clarify the potential oncogenic role of HPV in the onset of oral cancer.
References
Auluck A, Hislop G, Bajdik C, et al. Trends in oropharyngeal and oral cavity cancer incidence of human Papillomavirus (HPV)-related and HPV-unrelated sites in a multicultural population: the British Columbia experience. Cancer 2010 Mar 24.
Badaracco G, Rizzo C, Mafera B, et al. Molecular analyzes and prognostic relevance of HPV in head and neck tumors. oncol. Rep. 2007 Apr;17(4):931-9.
Castro TP, Bussoloti Filho I. Prevalence of human papillomavirus (HPV) in oral cavity and oropharynx. Braz J Otorhinolaryngol. 2006 Mar-Apr;72(2):272-82.
Chaudhary AK, Singh M, Sundaram S, Mehrotra R. Role of human papillomavirus and its detection in potentially malignant and malignant head and neck lesions: updated review. Head & Neck Oncology 2009; 1:22
Chocolatewala NM, Chaturvedi P. Role of human papilloma virus in the oral carcinogenesis: an Indian perspective. jCancer Res Ther. 2009 Apr-Jun;5(2):71-77.
de Jong MC, Pramana J, Knegjens JL et al. HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors. Radiother. oncol. 2010 Mar 24.
Feller L, Khammissa R AG, Wood NH, Lemmer J. Epithelial maturation and molecular biology of oral HPV. Infectious Agents and Cancer 2009; 4:16
Furniss CS, McClean MD, Smith JF et al. Human papillomavirus 16 and head and neck squamous cell carcinoma. Int J Cancer. 2007 Jun 1;120(11):2386-92.
Goon P KC, Stanley MA, Ebmeyer J, et al. HPV & head and neck cancer: a descriptive update. Head & Neck Oncology 2009; 1:36.
Hennessey PT, Westra WH, Califano JA. Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications. J Dent Res. 2009 Apr;88(4):300-6.
Jo S, Juhasz A, Zhang K, Ruel C, et al. Human papillomavirus infection as a prognostic factor in oropharyngeal squamous cell carcinomas treated in a prospective phase II clinical trial. Anticancer Res. 2009 May;29(5):1467-74.
Kingsley K, Johnson D, O'Malley S. Transfection of oral squamous cell carcinoma with human papillomavirus-16 induces proliferative and morphological changes in vitro. Cancer Cell Int. 2006May; 22:6-14.
Lohavanichbutr P, Houck J, Fan W, et al. Genomewide gene expression profiles of HPV-positive and HPV-negative oropharyngeal cancer: potential implications for treatment choices. Arch Otolaryngol Head Neck Surg. 2009Feb;135(2):180-8.
Mannarini L, Kratochvil V, Calabrese L, et al. Human Papilloma Virus (HPV) in head and neck region: review of literature. Acta Otorhinolaryngologica Italica 2009; 29:119-126
Pintos J, Black MJ, Sadeghi N, et al. Human papillomavirus infection and oral cancer: a case-control study in Montreal, Canada. Oral Oncol. 2008 Mar;44(3):242-50.
Reddout N, Christensen T, Bunnell A, et al. High-risk HPV types 18 and 16 are potent modulators of oral squamous cell carcinoma phenotypes in vitro. Infectious Agents and Cancer 2007; 2:21.
Romanitan M, Näsman A, Ramqvist T, et al. Human papillomavirus frequency in oral and oropharyngeal cancer inGreece. Anticancer Res. 2008 Jul-Aug;28(4B):2077-80.
Ryerson AB, Peters ES, Coughlin SS, et al. Burden of potentially human papillomavirus-associated cancers of the Oropharynx and oral cavity in the US, 1998-2003. Cancer. 2008 Nov 15;113(10 Suppl):2901-9.
Schlecht NF. Prognostic value of human papillomavirus in the survival of head and neck cancer patients: an overview of the evidence. Oncol Rep. 2005 Nov;14(5):1239-47.
Smith EM, Ritchie JM, Pawlita M, et al. Human papillomavirus seropositivity and risks of head and neck cancer. Int J Cancer. 2007 Feb 15;120(4):825-32.
