STUDY OF THE HYPOLIPIDEMIC AND ANTI-INFLAMMATORY EFFECTS OF “YANTAK” DECOCTION IN PATIENTS WITH CORONARY HEART DISEASE AGAINST THE BACKGROUND OF STANDARD THERAPY

Authors

  • Tulabaeva G.M.
  • TalipovaY.Sh.
  • Sagatova H.M.
  • Abdukadirova N.M.
  • Khusanov A.A.

Keywords:

coronary heart disease, lipid profile, anti-inflammatory effect, quality of life, traditional medicine

Abstract

This article presents data on the use of "Yantak" decoction against the background of standard therapy of stable forms of coronary heart disease with hypolipidemic (by reducing the parameters of the atherogenic fraction and the tendency to increase the anti-atherogenic fraction), anti-inflammatory effects (trends in reducing the level of IL - 6 and highly specific CRP), and also demonstrated positive dynamics of clinical indicators to reduce the number of angina attacks and the need for nitroglycerin tablets. The dynamics of observation of patients with stable forms of coronary heart disease according to the results of the study showed an improvement in the parameters of the "quality of life" according to the results of the SF-36 questionnaire, this served as an additional condition for increasing adherence to therapy. The study's results showed the effectiveness of phytotherapy, which allowed, against the background of standard therapy, to improve the clinical prognosis in patients with high cardiovascular risk.

References

Almenova G.P. Medicinal property of Alhagi Pseudoalhagi Hill. from the family Fabaceae Lindl wild relatives of cultivated plants of Karakalpakstan - /Young researcher: challenges and prospects - Collection of articles on the materials of CCI international scientific and practical conference. Moscow, 2021, 86-88.

Arutyunyan T.V., Korystova A.F., Kublik L.N., Levitman M.H., Shaposhnikova V.V., Appazov N.O., Narmanova R.A., Ibadullaeva S.J, Korystov Y.N. Camel stickleback extract reduces angiotensin-converting enzyme activity in rat aorta increased in aging animals and their consumption of NO synthase inhibitor - // Bulletin of Experimental Biology and Medicine 2014, 8, 187-190.

World Health Organization (2013). WHO strategy for traditional medicine 2014-2023. World Health Organization. https://apps.who.int/iris/handle/10665/112501

Karomatov I.D., Akramova N.Sh. Nephroprotective properties of medicinal herbs - a literature review - //Biology and integrative medicine 2018, 11, 66-80.

Kosnazarov K.A., Romanova L.K., Meldebekova S.U. Medicinal and fodder value of camel's thorn - Alhagi Gagnev in the desert territory of Karakalpakstan - // Problems of modern science and education 2016, 7(49), 31-35.

Pleskanovskaya SA, Sopyev D., Khanova G.K., Rzakulieva O., Garabekova MA On the possibility of modulation of fibrinogenesis in athletes kickboxers by decoction of camel's stickleback (Alhagi Persarum L.) - //Actual problems of medicine - Materials of annual final scientific and practical conference Grodno 2018, 628-630.

Asghari M.H., Fallah M., Moloudizargari M., Mehdikhani F., Sepehrnia P., Moradi B. A Systematic and Mechanistic Review on the Phytopharmacological Properties of Alhagi Species.

//Anc. Sci. Life. 2016, Oct-Dec., 36(2), 65-71. doi: 10.4103/asl.ASL_37_16.

Fihn S.D., Gardin J.M., Abrams J. et al. 2012 ACCF/AHA/ACP/AATS/ PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Turgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation. 2012;126: e354-e471.

Young J.W.Jr., Melander S. Evaluating Symptoms to Improve Quality of Life in Patients with Chronic Stable Angina. Nurs Res Pract. 2013;504915. doi: 10.1155/2013/504915.

Oldridge N., Hofer S., McGee H., et al. The HeartQoL: Part I. Development of a new core health-related quality of life questionnaire for patients with ischemicheart disease. European Journal of Preventive Cardiology. 2014;21(1):90-97.

Beltrame J.F., Weekes A.J., Morgan C. et al. The prevalence of weekly angina among patients with chronic stable angina in primary care practices: the coronary artery disease in general practice (CADENCE) Study. Archives of Internal Medicine. 2009; 169:16:1491-1499.

Sumanen M. Occurance of symptoms and depressive mood and workingaged coronary heart disease patients. Health Qual Life Outcomes. 2004;8(2):60.

Schweikert B., Hunger M., Meisinger C. et al. Quality of life several years after myocardial infarction: comparing the MONICA/KORA registry to the general population. Eur Heart J. 2009;30(4):436-443.

Sheweita S.A., Mashaly S., Newairy A.A., Abdou H.M., Eweda S.M. Changes in Oxidative Stress and Antioxidant Enzyme Activities in Streptozotocin-Induced Diabetes Mellitus in Rats: Role of Alhagi maurorum Extracts. //Oxid. Med. Cell. Longev. 2016, 2016:5264064. doi: 10.1155/2016/5264064.

Downloads

Published

2023-06-01