FEATURES OF CEREBRAL VENOUS HEMODYNAMICS IN ACUTE CEREBROVASCULAR DISORDERS
Keywords:
Ischemic stroke, venous cerebral disfunction, cognitive impairment, reoencephalography, quality of lifeAbstract
282 patients who have diagnosed with ischemic stroke (IS) in the basin of the inner carotid artery (medium severity) were examined in the early recovery phase. In 237 patients was detected venous cerebral dysfunction (VCD) in various degrees which correlated with the expression of cognitive impairment, decreased memory and emotional response. VCD was determined according to the results of the questionnaires, reoencephalography and duplex scanning. Inversely proportional relationship between the VCD severity and the velocity of blood flow in the extra and intracranial arteries has also been identified. The effect of venous protective drugs on the quality of life and rehabilitation of patients after IS in the presence of VCD was studied at the second stage. Positive results have been determined, which make it possible to recommend these medicines for use in clinical practice.
References
Seifert H.A., Pennypacker K.R. Molecular and cellular immune responses to ischemic brain injury //Transactional Stroke Research. – 2014. – №5.-P. 543-553.
Silva N.A., Sousa N., Reis R.L. et al. From basics to clinical: A comprehensive review on spinal cord injury // progress in neurobiology. – 2014. – №114. – R.25-57.
TSO M.K., Macdonald R.L. Acute microvascular changes after subarachnoid hemorrhage and transient global cerebral ischemia // Stroke research and Treatment. – 2013. – №2013. – P.11-18.
Chen S., Chen Y., Xu L. et al. Venous system in acute brain injury: Methods of pathophysiological change and function // Experim. Neurol. – 2015. – №272. – R.4-10.
Kilik T., Akakin A. Anatomy of cerebral vehicles and sinuses //Frontiers of neurology and neuroscience. – 2008. – №23. – R.4-15.
Yu W., Rives J., Welch B. et al. Hyperplasia or exclusion of the ipsilateral cranial venous drainage is associated with early fatal edema of middle cerebral artery infarction //Stroke. – 2009. – №40. - R. 3736-3739.
Law M.N., Barco S., Coutinho J.M. et al. Cerebral venous thrombosis and thrombophilia: A systematic review and meta-analysis. //Semin Chromb Host. – 2013. – №39. - R. 913-927.
Li Q., Khatibi N., Zhang J.H. Vascular neural network: The importance of vehicle drag in stroke //Transactional Research. – 2014. – №5. – P. M163-166.
Semenov S.E., Kovalenko A.V., Moldavskaya I.V., etc. Diagnosis and role of cerebral venous fullness in the course and outcomes of non-hemorrhagic stroke // Complex problems of cardiovascular diseases. – 2014. – №3. – P. 108-117.
Gafurov B.G., Alikulova N.A., Nazarov J. A. The role of cerebral venous dysgemia in the formation of chronic cerebral circulatory insufficiency // Fundamental foundations of innovative development of science and education. – Penza, 2019. - 223-242.
