IMMUNOLOGICAL MECHANISMS – AS DIAGNOSTIC CRITERIA FOR TREATMENT OF NEUROPATHY IN CHILDREN

Authors

  • Akmal Ahmadjonovich GAYBIEV
  • Aziza Tahirovna DJURABEKOVA
  • Dilnoza Salimovna SHOMURODOVA

Keywords:

immune system, polineuropathy, antiganglioside antibodies, cyclophosphamide.

Abstract

The study examined 35 children with acute polyradiculoneuritis; In the course of molecular genetic research, antiganglioside antibodies were detected in the blood serum, which is a criterion for the differential diagnosis of acute polyradiculoneuritis. Against the background of traditional treatment, taking into account the data of immunological studies, the cyclophosphamide preparation was included in the treatment complex. Positive clinical and neurological dynamics confirmed the correctness of this treatment method.

References

Cross A.H., Golumbek P.T. Neurologic manifestations of celiac disease: proven, or just a gut feeling. Neurology. 2013. № 27. P. 1566-1568.

Kopishinskaya S.V., Gustov A.V. Neuromuscular disorders in celiac disease patients. European Journal of Neurology. 2010. Sep. P. 37-38.

Goddard C.J.R., Gillett H.R. Complications of celiac disease: are all pations at risk? Postgrad. Med. J. 2016. № 82. P. 705-712.

Koning F. The molecular basis of celiac disease. J. Mol. Recognit. 2003. № 16. P. 333-336.

Lepers S., Couignoux S., Colombel J.F., Dubucquoi S. Celiac disease in adults: new aspects. Rev. Med. Interne. 2004. № 25. P. 22-34.

Published

2021-06-23