SCIENTIFIC ANALYSIS OF THE ROLE OF C-REACTIVE PROTEIN AND HYPERGOMOCYSTEINEMIA IN CAUSE OF CHRONIC ISCHEMIC STROKE
Keywords:
C-reactive protein, hypercomocysteinemia, cognitive impairment, homocysteine.Abstract
The accumulation of homocysteine leads to loosening of the walls of the arteries, the appearance of local defects in the endothelium. Increased levels of C-reactive protein (CRP) and hypercomocysteinemia are considered as independent factors for the development of endothelial damage and atherosclerosis. This scientific article analyzes that C-reactive protein and homocysteine are major risk factors in the development of chronic ischemic stroke.
References
Семенова О.Н. Гипергомоцистеинемия у больных с хронической сердечной недостаточнос¬тью, жителей блокадного Ленинграда / О.Н. Семе¬нова, В.М. Шмелева, С.И. Ягашкина // Мед.-биол. и соц.-психол. пробл. безопасности в чрезв. ситу¬ациях. - 2008. - № 3 - С. 52-56.
Association between raised inflammatory markers and cognitive decline in elderly people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study / R.E. Marioni, M.W. Strachan, R.M. Reynolds [et al.] // Diabetes. - 2010. - Vol. 59, N 3. - P 710-713.
Association of C-reactive protein with mild cognitive impairment / R.O. Roberts, YE. Geda [et al.] // Alzheimers Dement. - 2009. - Vol. 5, N 5. - P 398-405.
Contribution of metabolic syndrome components to cognition in older individuals / M.G. Dik, C. Jonker [et al.] // Diabetes Care. - 2007. - Vol. 30, N 10. - P. 2655-2660.
C-reactive protein is linked to lower cognitive performance in overweight and obese women / V. Sweat, V Starr [et al.] // Inflammation. - 2008. - Vol. 31, N 3. - P. 198-207.
Elevated C-reactive protein is related to cognitive decline in older adults with cardiovascular disease / K.F Hoth, A.P Haley, J. Gunstad [et al.] // J. Am. Geriatr Soc. - 2008. - Vol. 56, N 10. - P. 1898-1903.
Elevated serum homocysteine level is not associated with serum C-reactive protein in patients with probable Alzheimer's disease / O. Lepara, A. Alajbegovic, A. Zaciragic [et al.] // J. Neural. Transm. - 2009. - Vol. 116, N 12. - P. 1651-1656.
Gimeno D. Inflammatory markers and cognitive function in middle-aged adults: the Whitehall II study / D. Gimeno, M.G. Marmot, A. Singh-Manoux // Psychoneuroendocrinology. - 2008. - Vol. 33, N 10. - P. 1322-1334.
High-sensitivity C-reactive protein and cognitive function in older women / J. Weuve, P.M. Ridker, N.R. Cook [et al.] // Epidemiology. - 2006. - Vol. 17, N 2. - P 183-189.
Peripheral levels of fibrinogen, C-reactive protein, and plasma viscosity predict future cognitive decline in individuals without dementia / R.E. Marioni, M.C. Stewart [et al.] // Psychosom. Med. - 2009. - Vol. 71, N 8. - P. 901-906.
Г.С.Рахимбаева М.К.Атаниязов Результаты операции каротидной эндартерэктомии при стенозирующих поражениях сонных артерий у больных с хронической ишемии головного мозга. “Тошкент Тиббиёт Академияси Ахборотномаси” илмий –амалий журнали, 2015, №4, С83-85
S. Bebitov G. Rakhimbaeva K. Mirzaeva Implication of C4d in progression of ischemic stroke on patients with lupus erythematosus. EAN 2015 Abstract. 2015 European Journal of Neurology,22 (Suppl. 1), 484-828
A. Umarov K. Daminova A. Prokhorova G. Rakhimbaeva Nitric oxide and c-reactive protein levels in ischemic stroke and ITS subtypes: correlation with clinical out¬come 25. European Stroke Conference 13-15 May 2016 in Venice, Italy Preliminary Programm Overview Р 158
Rakhimbaeva G.S. Akramov D.T. Akramova N.T. Subpunical atherosclerosis and cognitive impairment Ж.Неврология №3 2016 С.63
Xaydarov Nodirjon Kadirovich, Khaydarova Dildora Kadirovna. Clinical And Etiological Factors Of Atopic Stroke (Literature Review). NVEO - Natural Volatiles & Essential Oils. 2021.Р. 12049-12058
Khodjieva D. T., Khaydarova D. K. Clinical and neuroph clinical and neurophysiological ch ogical characteristics of teristics of post-insular cognitive disorders and issues of therapy optimization. Central Asian Journal of Pediatrics. Dec.2019. P 82-86
Хайдарова Д.Т., Хайдарова Д.К., Хайдаров Н.К. Характеристика поражений проводящих путей при умеренных когнитивных расстройствах на фоне хронической ишемии мозга. Евроазиатский Союз Ученых (ЕСУ). – 2015. - №7(16). – С. 97-98.
Маджидова Ё.Н., Хайдарова Д.К. Состояние мозгового кровообращения у пациентов с умеренными когнитивными расстройствами на фоне хронической ишемии мозга. Журнал неврология и нейрохирургия. 4 (28) 2015.Украина C.75-81.
