DYNAMICS OF QUALITY OF LIFE IN MONOTHERAPY OF SOME ANTICONVULSANTS IN PATIENTS WITH EPILEPSY: COMPARATIVE ANALYSIS
Keywords:
epilepsy, quality of life, anticonvulsantsAbstract
Epilepsy is a chronic disease that leads to various social and psychological consequences. Due to impact of epilepsy on the psychosocial status of patients, contributing to the formation of perception of their position in life, epilepsy is characterized by reduced quality of life. With purpose to evaluate the quality of life of epilepsy patients with estimating its dynamics on the background of monotherapy with some antiepileptic drugs studied 102 patients aged of 18-44 years. Using the methodology for assessing the quality of life of patients with epilepsy using QOLIE -31 questionnaire along with clinical, instrumental methods of examination is a reliable criterion for evaluating the additional efficacy and tolerability of therapy. To achieve a sufficient amount of research in this field, such studies requires further development , as it is a signal for physicians about available fears of patients and informs patients about the problems typical to their disease, facilitate interaction between physician and patient about the decision concerning tactics of diagnosis and treatment.
References
Авакян Г.Н. и соавт. Тактика ведения и дополнительные возможности терапии больных эпилепсией. Пособие для врачей – М.-2005.255с.
Белова А.Н. Шкалы, тесты и опросники в неврологии и нейрохирургии. Руководство для врачей. –М.-2004.187 с.
Гехт А.Б. Качество жизни больных эпилепсией. Международная конференция «Эпилепсия — диагностика, лечение, социальные аспекты». Москва.-2005; -С.120—125.
Гусев Е.И., Гехт А.Б. Эпилепсия: фундаментальные, клинические и социальные аспекты. Москва.- 2013.874с.
Незнанов Н.Г., Громов С.А., Михайлов В.А. и др. Эпилепсия, качество жизни, лечение. Ст-Петербург: // ВМА. -2005.-№3. -С.29-34.
Рудакова И.Г., Морозова О.С., Котов А.С. Влияние современных противоэпилептических препаратов на качество жизни больных эпилепсией //Журн. Неврол. и психиат. -2012.-№ 6(2). -С.-36-44.
Меликян Э.Г., Лебедева А.В., Мильчакова Л.Е., Гехт А.Б. Оценка различных методов исследования качества жизни у больных эпилепсией. //Журн. неврол и психиат. -2009.-№2(11). -С.17-22.
Карась А.Ю., Воскресенская О.Н. Факторы, влияющие на эффективность медицинской помощи и качество жизни у больных эпилепсией. //Вестник ВолГМ. -2007.- №1. -С.66-68
Новик А.А., Ионова Т.И. Руководство по исследованию качества жизни в медицине. 2-е издание. М: ОЛМА Медиагрупп, -2007.315 с
Canuet L., Ishii R., Iwase M. et al. Factors associated with impaired quality of life in younger and older adults with epilepsy. Epilepsy Res 2009; №1 (83). Р.-58-65.
Guekht A.B., Mitrokhina T.V., Lebedeva A.V. et al. Factors influencing on quality of life in people with epilepsy. Seizure. -2007.№ 2(16). -Р.128—133.
Jacoby A., Snape D., Baker G.A. Determinants of quality of life in people with epilepsy. //Neurol Clin.-2009. -№4 (27).-Р.43-63.
Laccheo I., Ablah E., Heinrichs R. et al. Assessment of quality of life among the elderly with epilepsy. Epilepsy Behav. 2008; Р.257—261.
Melykian E. et al. Health-related quality of life in Russian adults with epilepsy: the effect of socio-demographic and clinical factors. Epilepsy Behav. -2012 №25(4).-P.670-675
Mirzaeva K.S., Akbarkhodjaeva Z.A. Comparative analysis of some antiepileptic drugs with assessment of dynamics of quality of life in patient with epilepsy. TMA. -2014 №3. –P.5-12
Neznanov N.G., Mikhailov V.A., Kissin M.Ya. Social frustration and neurotic disorders in epilepsy. Epilepsy: translational, clinical and social aspects. Moscow. -2013. -P.-432-439.
Saetre E., Abdelnoor M., Perucca E. et al. Antiepileptic drugs and quality of life in the elderly: results from a randomized double-blind trial of carbamazepine and lamotrigine in patients with onset of epilepsy in old age. Epilepsy Behav. -2010 (3): -Р.395—401.
Tlusta E. et al., Clinical fnd demographic characteristics predicting QOL in patients with epilepsy in the Czech Repablic: how this can influence practice. Seizure. -2009. № 18(2). -P-85-90.