SYSTEMATIZATION OF POSTOPERATIVE COMPLICATIONS OF HOLMIUM LASER ENUCLEATION OF THE PROSTATE - A STANDARDIZED APPROACH

Authors

  • Giyasov Shukhrat Iskandarovich
  • Gafarov Rushen Refatovich

Keywords:

BPH, HoLEP, complications, systematization, Clavien-Dindo classification

Abstract

Purpose of the study. Evaluation of the efficacy and safety of holmium laser enucleation of the prostate (HoLEP) through the systematization of postoperative complications in patients with benign prostatic hyperplasia (BPH).Material and methods. The results of HoLEP in 40 patients with BPH were studied. The mean age of the patients was 65.0±1.1 years. Clavien-Dindo classification was used to adapt to the assessment of postoperative complications of HoLEP.Results. In order to highlight the border of an uncomplicated course of the postoperative period with a complicated course, the criteria for an uncomplicated postoperative period are unified. Postoperative complications were systematized according to the adapted Clavien-Dindo classification and the following data were obtained: a total of 28 (70%) complications were observed, of which: complications of I degree - 8 (28.6%), II degree - 16 (57.1%), IIIa degree - 3 (10.7%), degree IIIb - 1 (3.6%), degree IVa - 0, degree IVb - 0, degree V - 0. Conclusions. For an objective assessment of the quality of surgical interventions and systematization of complications using the Clavien-Dindo classification, it must first be adapted, taking into account the specifics of the method and the postoperative period. HoLEP is a highly effective and safe surgical treatment for BPH. The effectiveness of treatment reached 100% due to the absence of complications requiring additional reconstructive plastic interventions, as well as deaths.

References

Kim EH, Larson JA, Andriole GL (2016) Management of benign prostatic hyperplasia. Annu Rev Med 67:137–151.

Foster HE, Barry MJ, Dahm P, Gandhi MC, Kaplan SA, Kohler TS, et al. Surgical Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA Guideline. J Urol 2018;200:612–9.

Karavitakis M, Kyriazis I, Omar MI, Gravas S, Cornu JN, Drake MJ, et al. Management of Urinary Retention in Patients with Benign Prostatic Obstruction: A Systematic Review and Meta-analysis. Eur Urol 2019;75:788–98.

EAU Guidelines. Edn. presented at the EAU Annual Congress Milan 2021. ISBN 978-94-92671-13-4.

Serretta V, Morgia G, Fondacaro L, Curto G, Lo bianco A, Pirritano D, et al.; Members of the Sicilian-Calabrian Society of Urology. Open prostatectomy for benign prostatic enlargement in southern Europe in the late 1990s: a contemporary series of 1800 interventions. Urology 2002;60:623–7.

Mearini E, Marzi M, Mearini L, Zucchi A, Porena M. Open prostatectomy in benign prostatic hyperplasia: 10-year experience in Italy. Eur Urol 1998;34:480–5. 5. Gratzke C, Schlenker B, Seitz M, Karl A, Hermanek P, Lack N, et al. Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. J Urol 2007;177:1419–22.

Varkarakis I, Kyriakakis Z, Delis A, Protogerou V, Deliveliotis C. Long-term results of open transvesical prostatectomy from a contemporary series of patients. Urology 2004;64:306–10.

Reich O, Gratzke C, Bachmann A, Seitz M, Schlenker B, Hermanek P, Lack N, Stief CG; Urology Section of the Bavarian Working Group for Quality Assurance. Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol. 2008 Jul;180(1):246-9.

Gilling PJ, Cass CB, Malcolm AR, Fraundorfer MR. Combination holmium and Nd:YAG laser ablation of the prostate: initial clinical experience. J Endourol. 1995;9(2):151–3.

Gilling PJ, Kennett KM, Fraundorfer MR. Holmium laser resection versus transurethral resection of the prostate: results of a randomized trial with 2 years of follow-up. J Endourol. 2000;14(9):757–60.

Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibañes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009 Aug;250(2):187-96.

Dindo D., Demartines N., Clavien P.A. Classification of surgical

complications: a new proposal with evaluation in a cohort of 6336

patients and results of a survey. Annals of Surgery. 2004; 240:205-13.

De Cassai A, Boscolo A, Tonetti T, Ban I, Ori C. Assignment of ASA-physical status relates to anesthesiologists' experience: a survey-based national-study. Korean J Anesthesiol. 2019 Feb;72(1):53-59.

Loppenberg B, Noldus J, Holz A, Palisaar RJ. Reporting complications after open radical retropubic prostatectomy using the Martin criteria. J Urol 2010;184:944-8.

Rabbani F, Yunis LH, Pinochet R, Nogueira L, Vora KC, Eastham JA, et al. Comprehensive standardized report of complications of retropubic and laparoscopic radical prostatectomy. Eur Urol 2010;57:371-86.

Jeong J, Choi EY, Kim IY. Clavien classification of complications after the initial series of robot-assisted radical prostatectomy: The cancer institute of Jersey/Robert Wood Johnson medical school experience. J Endourol 2010;24:1457-61.

Ng CK, Kauffman EC, Lee MM et al (2010) A comparison of postoperative complications in open versus robotic cystectomy. Eur Urol 57:274–282.

Гиясов Ш.И., Акилов Ф.А. Трудности в систематизации послеоперационных осложнений эндоскопического лечения уролитиаза и пути их решения. Вестник урологии. 2018;6(1):5-17.

Sagen E, Namnuan RO, Hedelin H, Nelzén O, Peeker R. The morbidity associated with a TURP procedure in routine clinical practice, as graded by the modified Clavien-Dindo system. Scand J Urol. 2019 Aug;53(4):240-245.

Mbaeri TU, Abiahu JA, Obiesie EA, Odo C, Oranusi KC, Nwofor AME, Orakwe JC. Assessment of Complications of Transurethral Resection of the Prostate Using Clavien-Dindo Classification in South Eastern Nigeria. Niger J Surg. 2020 Jul-Dec;26(2):142-146.

Yalçın S, Yılmaz S, Gazel E, Kaya E, Aydoğan TB, Aybal HÇ, Tunç L. Holmium laser enucleation of theMitr prostate for the treatment of size-independent BPH: A single-center experience of 600 cases. Turk J Urol. 2020 Jan 17;46(3):219-225.

Published

2022-06-27