MICROFLORA IN CHRONIC POLYPOUS SINUSITIS

Authors

  • NASRETDINOVA Mahzuna Taxsinovna
  • OMONOVA Maftuna Shavkat qizi

Keywords:

chronic polypous sinusitis, microflora, antibiotics pathogenic chromogenic staphylococcus

Abstract

170 patients of different age with chronic polypous sinusitis have undergone surgical and medicamentous sanation of the nasal cavity and paranasal sinuses. In al! the cases microflora of the middle nasal passage was studied as well as pathogenic properties of the causative agents, their sensitivity to antibiotics, lysis by phages, and data were correlated to the clinical data. Obtained results suggested a considerable staphylococcal dissemination of the nasal mucosa in presence of polypous sinusitis that increased in the early postoperative period and somewhat decreased in 6—12 months postsurgically. Pathogenic chromogenic staphylococcus (especially of phage group I) was associated with more serious course of disease with frequent recurrences of nasal polyposis. Microbial associations in suppurative-and-polypous sinusitis were isolated 2 times more often than in polypous one.

References

Bachert C, Gevaert P, Holtappels G, Johansson SG, van Cauwenberge P. Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol. 2001;107(4):607-614. doi:10.1067/mai.2001.112374.

Bachert C, Zhang N, Holtappels G, De Lobel L, van Cauwen- berge P, Liu S, Lin P, Bousquet J, Van Steen K. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immu nol. 2010;126(5):962-968. doi: 10.1016/j.jaci.2010.07.007.

Bhattacharyya N., Kepnes L. J. Medications prescribed at ambulatory visits for nasal polyposis. Am J Rhinol Allergy. 2013;27:479-481. DOI: 10.2500/ajra.2013.27.3969

Bolger WE, Butzin CA, Parsons DS. Paranasal sinus bony anatomic variations and mucosal abnormalities: CT analysis for endoscopic sinus surgery. Laryngoscope. 1991;101:56-64. doi:10.1288/00005537-199101000-00010..

Budkovaya M. A. Kompleksnaya otsenka immunologicheskikh i fiziologicheskikh aspektov pri lechenii polipoznogo rinosinusita [Complex evaluation of immunological and physiological aspects in the treatment of polypous rhinosinusitis. Rossiiskaya otorinolaringologiya. 2015. (S1): 34–41 (in Russ) .

Bunnag C, Pacharee P, Vipulakom P, Siriyananda C. A study of allergic factor in nasal polyp patients. Ann Allergy. 1983;50(2):126- 132.

Savlevich E.L., Dyneva M.E., Gaganov L.E. Egorov V.I., Gerasimov A.N., Kurbacheva O.M. Treatment and diagnostic algorithm in different phenotypes of polyposis rhinosinusitis. Russian allergologic journal. 2019;16(2):50-60. (in Russ).

Polatova Djamila , Madaminov Ahmad, Raximov Nodir . Significance of expression PD-L1 and p53 proteins in human papillomavirus-associated oropharyngeal squamous cell carcinoma// Journal of Biomedicine and Practice. 2022, vol . 7, issue 4, pp . 144-151

Abdurakhmonov F. R., Rakhimov N. M., Abdurakhmonova F. F. Special choices for the treatment of complications of the soft tissue injuries of the facial region //The American Journal of Medical Sciences and Pharmaceutical Research. – 2023. – Т. 5. – №. 10. – С. 24-26.

Published

2024-12-24