EVALUATION OF RADIATION DOSE LOAD TO ORGANS AT RISK WHEN SWITCHING TO A HYPOFRACTIONATED REGIMEN OF POSTOPERATIVE RADIOTHERAPY FOR LEFT BREAST CANCER
Keywords:
radiotherapy, breast cancer, quantitative analysis, hypofractionated radiotherapy, standard fractionation regimenAbstract
In planning radiotherapy for oncology patients, the selection of the single fraction dose is considered one of the key factors influencing treatment efficacy. When the single fraction dose (SFD) is 2 Gy, the total dose (TD) reaches 50 Gy, whereas with an SFD of 2.66 Gy, the total dose equals 42.56 Gy. All these parameters significantly affect the pattern of radiation dose distribution to the target volume and organs at risk.
Hypofractionated radiotherapy is defined as an increase in the dose per fraction with a simultaneous reduction in the total number of treatment sessions. One of the main advantages of hypofractionation is the reduction in the overall duration of radiotherapy without compromising treatment effectiveness, which in turn decreases the workload of radiotherapy departments (1,2).
In postoperative radiotherapy for breast cancer, one of the key criteria for optimal treatment planning is the assessment of radiation dose exposure to organs at risk, including the lungs, heart, and spinal cord.
Objective. To evaluate radiation dose exposure to organs at risk in patients with breast cancer undergoing postoperative radiotherapy when transitioning from standard fractionation with a single fraction dose of 2 Gy (25 fractions) to an increased single fraction dose of 2.66 Gy (16 fractions).References
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