COMBINED ENDOVASCULAR INTERVENTIONS FOR LESIONS OF THE PERIPHERAL ARTERIES OF THE LOWER EXTREMITIES ON THE BACKGROUND OF DIABETES MELLITUS
Keywords:
diabetes, critical ischemia, prolonged intra-arterial catheter therapy, purulent-necrotic wound, gangreneAbstract
The aim of the study assess the effectiveness of minimally invasive methods in the treatment of patients with gangrene of the lower extremities against the background of diabetes mellitus.
Materials and research methods. The results of the study and inpatient treatment of 311 patients were analyzed with purulent-necrotic complications of DFS in the department of purulent surgery and surgical complications of diabetes at the 2nd clinic of the Tashkent Medical Academy. All patients suffered from type 2 diabetes.
Research results. The performance of an adequate isolated revascularization of the peripheral arteries of the extremities and the complex of therapeutic measures carried out in 81.0% of cases led to the preservation of the support function of the limb. The catheterization of the NLA with the conduct of PIACT improved the result by 7.3% and this shows the effectiveness of the integrated use of minimally invasive treatment methods for gangrene of the lower extremities against the background of diabetes mellitus.
Conclusions. Revascularization of the lower limb arteries is a highly effective method of treatment in the rescue of the limb in patients with diabetic gangrene of the lower extremities and, in the presence of purulent-necrotic processes against the background of critical ischemia of the foot, in 81.0% of cases it will be possible to save the limb.
References
Abyshov N.S., Zakirjayev E.D. The immediate results of “large” amputations in patients with occlusive diseases of lower limb arteries // Surgery. Journal them. N.I. Pirogov. –2015.– №11. - P.15-19.
Gaibov A.D., Gaibov A.D., Kamolov A.N. Amputations of the lower limbs during their chronic critical ischemia // Cardiology and cardiovascular surgery. – 2019. – №2. - C.40-46.
Zoloev G.K. Obliterating diseases of the arteries. Surgical treatment and rehabilitation of patients with loss of limb // M .: Medicine. – 2018. – 432 p.
Pokrovsky A.V., Zotikov A.E. Prospects and reality in the treatment of atherosclerotic lesions of the aorta // M .: Meditsina. – 2018.-192 p.
Saveliev B.C., Koshkin B.C., Karalkin A.B. Pathogenesis and conservative treatment of severe stages of atherosclerosis obliterans of lower limb arteries // M .: MIA. –2020. – 214 p.
Biamino G. et al. Critical limb ischemia: new techniques for complex interventions // HMP Communication. –2021. –P. 72.
Castelli G. et al. Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction // Critical Care.–2017.–Vol. 8.–P. 234-242.
Dormandy J.A. et al. Major amputations // Semin Vase. Surg.–2009 –Vol. 73.–P. 321.
Eskelinen E. et al. Major amputation incidence decreases both in non-diabetic and in diabetic patients in Helsinki // Scandinavian Journal of Surgery.–2020.–Vol.95.– P. 185-189.
Johannesson A. et al. Incidence of lower-limb amputation in the diabetic and nondiabetic general population // Diabetes Care.–2021.–Vol.32.– №2.– P.275–280.
Snow D.E., Everett J., Mayer G. et al. The presence of biofilm structures in atherosclerotic plaques of arteries from legs amputated as a complication of diabetic foot ulcers // J. Wound Care. – 2016. – Vol. 25, №2. - S16-22.
TASC Working group. Management of peripheral arterial disease (PAD): TransAtlantic Inter- Society Consensus (TASC). Management Eur // J. Vasc. Endovasc. Surg. – 2007– Vol. 19, Suppl 1.
Zhang Z., Lv L. Effect of local insulin injection on wound vascularization in patients with diabetic foot ulcer // Exp. Ther. Med. – 2018. – Vol. 11, №2. – P.397-402.