CONGENETAL DEFECTS AND ANOMALIES OF GALL BLADDER DEVELOPMENT IN CHILDREN

Authors

  • ALIYEV Mahmud Muslimovich
  • NEMATJONOV Farrux Zokirzjon o’gli
  • TUYCHIEV Golibjon Urmonjonovich
  • TUYCHIEV Sherozbek Urmonovich

Keywords:

gallbladder, bile duct, diverticul, hypoplasia, agnesia

Abstract

While congenital defects of the gallbladder are rare compared to other congenital defects of the biliary system, variants of developmental anomalies are significantly more numerous and have a long history. According to the observational results of some authors, the number of birth defects of the gall bladder in 50 years of research did not even reach 50 people. Bronshtein (1993) in the examination of 10016 fetuses at the age of 14 weeks found birth defects of the Gallbladder in only 0.15%, while Tumanyan conducted analyzes in 616 children and managed to identify structural disorders of the Gallbladder in 2/3 of them. Some congenital defects that do not clinically affect the movement of bile fluid in the gallbladder may not be separated into a nosological unit.

In the report of ultrasound examination, which is the main examination method for the diagnosis of congenital defects of the gallbladder, some authors have suggested the use of CT, MRT and MRXPG examinations according to the guidelines. It should be mentioned that children of all ages with symptoms of chronic cholecystitis should be thoroughly examined. Although the main treatment of these birth defects is focused on conservative procedures, in each case, surgery is indicated only in complicated cases. The laparoscopic approach can be used more for diagnostic purposes and in some cases as a therapeutic procedure based on laparoscopic findings.

References

Aliev M.M., Yuldashev R.Z. “Surgical hepatology of childhood” Monograph. Tashkent, 2017. (in Uzb)

Aliev M.M., Nematjanov F.Z., Toychiev G'.O'.., Yuldashev R.Z,. "Epidemiology of obstructive cholestasis in children". Journal of Biomedicine and Practice. Volume 7. Number 6. Tashkent 2022. (in Uzb)

Freund G.G.. Sokolov Yu.Yu. Morphogenesis of duodenopancreatobiliary anomalies in children. Permian. 2003. P.14. (in Uzb)

Morozov D.A., Gusev A.A., Pimenova E.S. “Bile duct cysts: modern aspects of surgical treatment and clinical observation of a rare variant.” 06/29/2015 412-415. (in Uzb)

Mayboroda Yu.N. Development of bile and pancreatic ducts and their nervous apparatus in human embryogenesis. Author's abstract. dis. Ph.D. medical sciences - Yaroslavl. – 1979. – P.23. (in Uzb)

Mukhina Yu.G., Degtyareva A.V., Morozov I.A. and others. Pathophysiological basis of the formation of neonatal cholestasis // Lectures on pediatrics. – T.3. – Gastroenterology. – M. – 2003. – P.179-191. (in Uzb)

Razumovsky A.Yu, Rachkov V.E. “Biliary tract surgery in children” manual for doctors. Moscow 2020. (in Uzb)

Iryshkin O.E., Ilyinsky I.M., Tsirulnikova O.M., Gauthier S.V.Etiology, pathogenesis and morphology of biliary atresia. Bulletin of Transplantology and Artificial Organs volume xiv No. 3–2012. 69-76 pp. (in Uzb)

Tumanyan G.T. Diagnosis and surgical treatment of developmental anomalies of the gallbladder and bile ducts in children: dis med nak M Vidar 2009. 139 pages. (in Uzb)

Sokolov Yu.Yu. Diagnosis and surgical treatment of duodenopancreatic anomalies in children. Dissertation.doc. med. sc. Perm. 2003. P.66. (in Uzb)

Popandopulo N.S. The significance of anatomical variants and congenital anomalies of the extrahepatic biliary system in the development of chronic cholecystitis: Dis. Ph.D. medical sciences – Krasnoyarsk – 1996. – P. 140. (in Uzb)

Bronshtein M., Weiner Z., Abramovich H., et al. Prenatal diagnosis of gallbladder anomalies, report of 17 cases// Prenat diagnos.1993. vol 13, N 9. P 851-861. (in Uzb)

Bittman S., Ulus H., Springer A. Combined pentalogy of cabtrell with tetralogy of Fallot, gall bladder agnesis and polysplenia: a case report. // J.Pediatric Surg. 2004. Vol 39, N 1. P 107-109. (in Uzb)

Dogonay S., Kocacoc E., EsenM. True diverticulum of the gallbladder//J ultrasound. Med. 2011. Vol 29. P 121-123. (in Uzb)

Dubois A.M. The embryonic liver. In: RouillerC., editor. The liver. New York: Academic Press. 1963.P.1-39. (in Uzb)

Calder n., Carnerio H., Khwaja H., Thompson J.N. Gallbladder agnesis with midgut malorotation// BMJ case Rep. 2012. Vol 2012. Pi.bcr.10.2011.5053. (in Uzb)

Gross R. Conginetal anomalies of the gallbladder: a review of 148 cases with report of a double gallbladder// Arch.Surg. 1936. Vol 32. P 131-162. (in Uzb)

Hasan M.M., Reza E., Khan M.R., et al. Anatomical and conginental anomalies of extra hepatic biliary system encountred during cholesystoectomy/ Mymensing Med.J. 2013. Vol 22, N 1. P 20-26. (in Uzb)

Kosmidis K., Koimtzis G., Kosmidou M., et al. Gallblader hypoplasia, a conginental abnormality of the gallbladder: case report. Am.J.Case report. 2017. Vol 18. P 1320-1324. (in Uzb)

Kasi P., Ramirez R., Rogal S et al. gallbladder agnesis// case report. Gastroenterol. 2011. Vol 5, N 3. P 654-662. (in Uzb)

Lee T., Park S., Park J. Gallbladder pseudodiverticulosis mimicking a multiseptate gallbladder withstones//Gut liver.2009. Vol 3, N 2. P 134-136. (in Uzb)

Malde S. Gallbladder agnesis diagnosed intra operatively a case report// J.Med. case report. 2010. Vol 4. P 285. (in Uzb)

Nouoira F., Taeib C., Hela L et al. Duplication of gall bladder// Tunis Med.2011. Vol 89, N 10. P 798-799. (in Uzb)

Nganuma S., Ishida H., Konno K. et al. Sonographic findgis of anomalus position of the gallladder. Abdomen imaging. 1998. Vol 23. P 67-72. (in Uzb)

Nagai M., Kubota K., Kawasaki K. Are left sided gallbladders really located on the left side// Ann Surg 1997. Vol 255. P 274-280. (in Uzb)

Menon P, Rao K.L, Thapa B.R et al . Duplicated gall bladder with duodenal duplication cyst// J.Pediatr Surg. 2013. Vol.48, N 4. P 25-28. (in Uzb)

Todani T, Watanabe Y, Narusue M et al. Congenital bile duct cysts: Classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst. Am J Surg. 1977;134:263-269. (in Uzb)

Tan C.E., Moscoso G.J. The developing human biliary systemat the portahepatis level between 11 and 25 weeks of gestation: a way to understanding biliaryatresia. Part2 // Pathol. Int. 1994. Vol.44.№8. P.600-610.66. (in Uzb)

Tan C.E., Moscoso G.J. The developing human biliary systemat the portahepatis level between 29 days and 8 weeks ofgestation: a way to understanding biliary atresia. Part 1 // Pathol. Int. – 1994. – Vol.44. - №8. – P.587-599. (in Uzb)

Thapar P., Masurkar V., Phili R et al. Rudimentary gallbladder imiks choledochal cyst Indian J.Surg. 2015. Vol 77. N 2. P 726-728. (in Uzb)

Turkvatan A., Erden A., Celik M., Olcer T. Ectopic hypoplastic and multiseptate gallbladder with coexisting choledochal cyst: evalution with sonography and magnetic resonance chalangiopancreatography. J.Clin.Ultrasound. 2006.Vol 34. N 2. P 88-91. (in Uzb)

Wahlby L. Aplasia of the gallbladder with cammon ducts stones// Acta Chir. Scand. 1977. Vol 143, N 4. P 241-243. (in Uzb)

Статья поступила в редакцию 11.09.2023; одобрена после рецензирования 21.10.2023; принята к публикации 25.10.2023.

The article was submitted 11.09.2023; approved after reviewing 21.10.2023; accepted for publication 25.10.2023.

Информация об авторах

Алиев Махмуд Муслимович, Тошкентский педиатрический медицинский институт, профессор кафедры детской хирургии, доктор медицинских наук, mahmudali47@list.ru, ORCID 0000-0002-3923-2496.

Нематжонов Фаррух Зокиржон угли, Андижанский государственный медицинский институт, ассистент кафедры детской хирургии, drurologfarrukh@mail.com, ORCID 0000-0003-4610-2558.

Туйчиев Голибжон Урмонжонович, Андижанский государственный медицинский институт, доцент кафедры детской хирургии, кандидат медицинских наук, golibjontuychiyev1964@gmail.com, ORCID 0000-0002-4485-9226.

Туйчиев Шерозбек Ғолибжон ўғли, Андижанский государственный медицинский институт, ассистент кафедры стоматологичский хирургии, golibjontuychiyev1964@gmail.com, ORCID 0009000989828122.

Источники финансирования: Работа не имела специального финансирования.

Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.

Вклад авторов:

Алиев М.М. — идеологическая концепция работы, написание текста; редактирование статьи;

Нематжонов Ф.З., Туйчиев Г.У., Туйчиев Г.У — сбор и анализ источников литературы, написание текста.

Information about the authors

Aliyev Mahmud Muslimovich, Tashkent Pediatric Medical Institute, Professor of the Department of Pediatric Surgery1, mahmudali47@list.ru, ORCID 0000-0002-3923-2496.

Nematjonov Farrukh Zokirzhon ugli, Andijon state medical isnstitute, Department of Pediatric Surgery, Assistant, drurologfarrukh@mail.com, ORCID 0000-0003-4610-2558.

Tuychiev Golibzhon Urmonzhonovich, Andijon state medical isnstitute, Department of Pediatric Surgery, Candidate of Medical Sciences, golibjontuychiyev1964@gmail.com, ORCID 0000-0002-4485-9226.

Tuychiev Sherozbek Urmonovich, Andijon state medical isnstitute, Department of Stomatologic Surgery, Assistant, golibjontuychiyev1964@gmail.com, ORCID 0009-0007-4995-4920.

Sources of funding: The work did not receive any specific funding.

Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.

Contribution of the authors:

Aliyev M.M — ideological concept of the work, writing the text; editing the article;

Nematjonov F.Z., Tuychiyev G.U., Tuychiyev G.U — collection and analysis of literature sources, writing the text.

Published

2024-01-30