BASICS OF MORPHOFUNCTIONAL FEATURES OF FORMATION AND DIFFERENTIATION OF IMMUNE CELLS OF THE SMALL INTESTINE
Keywords:
morphology, antigenic differentiation, lymphoid structures, small intestine, B and T lymphocytes, macrophage, epithelial cells, Peyer's patchesAbstract
Immune cells of the small intestine are a unique and understudied population of cells that perform immune defense functions. These cells are distributed in the epithelium of the mucosa of the small intestine and have the ability to detect pathogens and regulate metabolic and immune processes in the alimentary canal. This article reviews and discusses key aspects of the immune cells of the small intestine, including their morphology, function, and role in maintaining body homeostasis. We also review ongoing research aimed at elucidating the molecular mechanisms underlying these cellular effects and their potential implications for the development of new approaches in therapeutic practice and immunology. The article provides an overview of the main aspects related to the immune cells of the small intestine and emphasizes their importance in the context of the functioning of the immune system and the regulation of metabolic processes in the body. This line of research has the potential to identify new effective learning methods and is of interest for clinical practice and scientific research.
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Статья поступила в редакцию 05.11.2023; одобрена после рецензирования 23.12.2023; принята к публикации 25.12.2023.
The article was submitted 05.11.2023; approved after reviewing 23.12.2023; accepted for publication 25.12.2023.
Информация об авторах:
Орипов Фирдавс Суратович- д.м.н., профессор, заведующий кафедры гистологии, цитологии и эмбриологии. Самаркандский государственный медицинский университетт, Самарканд, Узбекистан. Е-mail: firdavs.oripov1809@gmail.com, https://orcid.org/0000-0002-0615-0144
Мирзаева Сарвиноз Содиковна- самостоятельный соискатель кафедры гистологии, цитологии и эмбриологии. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: sara301228@gmail.com, https://orcid.org/0009-0008-6457-5643
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Орипов Ф.С. — идеологическая концепция работы, написание текста; редактирование статьи;
Мирзаева С.С. — сбор и анализ источников литературы, написание текста.
Information about the authors:
Dilnoza A. Khasanova — DSc, professor, head of the Department of Histology, Cytology and Embryology. Samarkand State Medical University. Samarkand, Uzbekistan; E-mail: firdavs.oripov1809@gmail.com, https://orcid.org/0000-0002-0615-0144
Sarvinoz S. Mirzayeva — independent candidate of the Department of Histology, Cytology and Embryology. Samarkand State Medical University, Samarkand, Uzbekistan; Е-mail: sara301228@gmail.com, https://orcid.org/0009-0008-6457-5643
Sources of funding: The work did not receive any specific funding.
Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.
Contribution of the authors:
Oripov F.S. — ideological concept of the work, writing the text; editing the article;
Mirzayeva S.S. — collection and analysis of literature sources, writing the text.
