INGICHKA ICHAK IMMUN HUJAYRALARINING SHAKLLANISHI VA IXTISOSLASHUVINING MORFOFUNKSIONAL ASOSLARI
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morfologiyasi, antigen ixtisoslashuvi, limfoid tuzilmalar, ingichka ichak, B va T limfotsitlar, makrofag, epiteliy hujayralari, Peyer pilakchalari##article.abstract##
Ingichka ichakning immun hujayralari immunitetni himoya qilish funksiyalarini bajaradigan noyob va kam o'rganilgan hujayralar populyatsiyasidir. Bu hujayralar ingichka ichak shilliq qavatining epiteliysida tarqalgan va patogenlarni aniqlash va ovqat hazm qilish kanalida metabolik va immun jarayonlarni tartibga solish qobiliyatiga ega. Ushbu maqolada ingichka ichakning immun hujayralarining asosiy jihatlari, shu jumladan ularning morfologiyasi, funksiyalari va tananing gomeostazini ta'minlashdagi roli ko'rib chiqiladi va muhokama qilinadi. Shuningdek, biz ushbu hujayralar ta'siri ostida yotgan molekulyar mexanizmlarni va ularning terapevtik amaliyot va immunologiyada yangi yondashuvlarni ishlab chiqish uchun potensial oqibatlarini ochib berishga qaratilgan davom etayotgan tadqiqotlarni ko'rib chiqamiz. Maqolada ingichka ichakning immun hujayralari bilan bog'liq bo'lgan asosiy jihatlar haqida umumiy ma'lumot berilgan va ularning immunitet tizimining ishlashi va organizmdagi metabolik jarayonlarni tartibga solish kontekstidagi ahamiyati ta'kidlangan. Ushbu tadqiqot yo'nalishi yangi samarali o'rganish usullarini aniqlash imkoniyatiga ega va klinik amaliyot va ilmiy tadqiqotlar uchun qiziqish uyg'otadi.
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Статья поступила в редакцию 05.11.2023; одобрена после рецензирования 23.12.2023; принята к публикации 25.12.2023.
The article was submitted 05.11.2023; approved after reviewing 23.12.2023; accepted for publication 25.12.2023.
Информация об авторах:
Орипов Фирдавс Суратович- д.м.н., профессор, заведующий кафедры гистологии, цитологии и эмбриологии. Самаркандский государственный медицинский университетт, Самарканд, Узбекистан. Е-mail: firdavs.oripov1809@gmail.com, https://orcid.org/0000-0002-0615-0144
Мирзаева Сарвиноз Содиковна- самостоятельный соискатель кафедры гистологии, цитологии и эмбриологии. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: sara301228@gmail.com, https://orcid.org/0009-0008-6457-5643
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Орипов Ф.С. — идеологическая концепция работы, написание текста; редактирование статьи;
Мирзаева С.С. — сбор и анализ источников литературы, написание текста.
Information about the authors:
Dilnoza A. Khasanova — DSc, professor, head of the Department of Histology, Cytology and Embryology. Samarkand State Medical University. Samarkand, Uzbekistan; E-mail: firdavs.oripov1809@gmail.com, https://orcid.org/0000-0002-0615-0144
Sarvinoz S. Mirzayeva — independent candidate of the Department of Histology, Cytology and Embryology. Samarkand State Medical University, Samarkand, Uzbekistan; Е-mail: sara301228@gmail.com, https://orcid.org/0009-0008-6457-5643
Sources of funding: The work did not receive any specific funding.
Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.
Contribution of the authors:
Oripov F.S. — ideological concept of the work, writing the text; editing the article;
Mirzayeva S.S. — collection and analysis of literature sources, writing the text.
