SPINAL ANESTEZIYANING QANDLI DIABET BILAN KASALLANGAN BEMORLARDA QT INTERVALINING UZAYISHIGA TA'SIRI
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To'g'rilangan QT intervali, Qandli Diabet, Uzun QT Sindromi, Spinal Anesteziya, Spinal Blokada##article.abstract##
Ushbu tadqiqotning maqsadi qandli diabet bilan kasallangan va qandli diabet bilan kasallanmagan bemorlarda spinal anesteziyaning QTc intervaliga ta'sirini o'rganish, spinal anesteziya va avtonom nevropatiyaning QTc intervalining uzayishiga bo'lgan ma'lum ta'sirini hisobga olishdan iborat. Spinal anesteziya va avtonom nevropatiya, qandli diabet fonida kuzatiladigan, QTc intervalining uzayishiga bog'liq. Biroq, qandli diabet bilan kasallangan bemorlarda spinal blokadaning QTc intervalining davomiyligiga aniq ta'siri bugungacha chuqur o'rganilmagan. Biz qandli diabetga ega bemorlarda spinal blokadaning natijasida kelib chiqadigan QTc intervali o’zgarishlari va qandli diabet bilan og’rimagan bemorlarga qaraganda QTc intervalining kattaroq uzayishi kuzatilishini o’rgandik. Ushbu istiqbolli kuzatuv tadqiqoti uchinchi darajali universitet klinikasida: SamDTU ko'p tarmoqli klinikasida o'tkazildi, 48 ishtirokchi ikki guruhga bo'lingan: qandli diabet bilan (DM guruhi, n=24) va qandli diabet bilan kasallanmagan (nazorat guruhi, n=24). Barcha ishtirokchilarga spinal anesteziya qo’llanildi. QTc intervali, T to'lqinining cho'qqisidan oxirigacha bo'lgan interval (Tp-e intervali), yurak urishining o'zgaruvchanligi, qon bosimi va yurak urish tezligi boshlang'ich holatda (T1) va spinal blokadadan keyin 1 (T2), 5 (T3) va 10 daqiqalarda (T4) qayd etildi. Bizning topilmalarimiz qandli diabetga ega bemorlarda spinal anesteziyadan keyin qandli diabet bilan chalinmagan bemorlarga qaraganda aniqroq QTc intervalining uzayishi sodir bo’lishini ko'rsatadi. Ushbu natijalar qandli diabetga ega bemorlarda yurakning elektr faoliyatini kuzatishning muhimligini ta'kidlaydi.
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