LATENT SIL INFEKTSIYASI FAOL SILGA PROGRESSIYA BO`LGAN BOLALARDA EPIDEMIOLOGIK, BIOLOGIK ANAMNEZ VA IJTIMOIY HOLAT KO`RSATGICHLARI
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latent sil infektsiyasi, xavf omillari, faol sil, bolalar, sil infektsiyasining o'chog'i##article.abstract##
Bugungi kun nuqtai nazaridan, latent sil infeksiyasini erta aniqlash va bolada yashirin va faol sil infektsiyasi o'rtasidagi differentsial diagnostika uchun oltin standartlar mavjud emas. Tadqiqot maqsadi: bolalarda latent sil infektsiyasi rivojlanishi va silning faol davrida somatik patologiyaning tuzilishi va epidemiologik anamnezining xususiyatlarini o'rganish. Materiallar va usullar: Xalqaro STROBE standartiga muvofiq retrospektiv-prospektiv kogort tadqiqoti o'tkazildi. 60 nafar bola tanlab olindi va uch guruhga bo‘lindi: 1-guruhga latent sil kasalligi bilan kasallangan 40 nafar, 2-guruhga faol sil kasalligi bilan kasallangan 20 nafar bola kiritildi. 1-guruh quyidagilarga bo'linadi: I kichik guruh, ularda latent sil infektsiyasining faol silga o'tishi aniqlangan 20 nafar bola va II kichik guruh, 20 nafar boladan iborat bo'lib, ularda latent sil infektsiyasi faol sil kasalligiga o'tmagan. Natijalar va muhokama. Ijtimoiy xavfning hal qiluvchi omillari bolaning kam ta'minlangan (RR 5,000), katta (RR 4,667) yoki to'liq bo'lmagan oilada (RR 3,200) yashashi, bola va uning oilasi uchun qoniqarsiz yashash sharoitlari (RR 4,857) va otaning doimiy ish joyining yo'qligi (RR 3,467), ota-onalar o'rtasida o'rta yoki o'rta maxsus ma'lumot darajasi (RR 3,000), onalar ishsizligi (RR 2,308), ota-onalarning ichkilikbozlik, chekish va giyohvand moddalarga qaramligi (RR 2,000) va bizning tadqiqotimizda bolaning "tartibsizligi" ning ijtimoiy omili ko'pincha mavjud edi (RR 2,000). Faol sil kasalligining rivojlanishi uchun xavf omillari bo'lishi mumkin bo'lgan somatik kasalliklarni hisobga olgan holda, biz quyidagi natijalarga erishdik: gijja invaziyasi (RR 3,000), temir tanqisligi anemiyasi (RR 1,900), endokrinologik patologiya va metabolik kasalliklar (RR 1,200), miopiya (RR 1,429), gastrit va kolit (RR 2,286), revmatizm va osteomielit (RR 2,000), pielonefrit (RR 1,333), buyrak gidronefrozi (RR 3,000). Shuni ta'kidlash kerakki, yuqorida sanab o'tilgan patologik sharoitlar, shuningdek, yashirin sil infektsiyasiga moyil bo'lgan omillar bo'lib xizmat qilgan. Biroq, bu guruhda biz qo'shimcha ravishda nafas olish patologiyasi (bronxial astma, allergik rinit) (RR 0,500) kabi omilning ahamiyatini aniqladik. Xulosa. O‘zbekiston Respublikasida latent sil kasalligiga chalingan bolalarni davolash taktikasini takomillashtirish maqsadida ilgari o`rganilgan xavf omillarining prognostik ahamiyatini baholash, shuningdek, yangi, zamonaviy omillarni aniqlash bo‘yicha ushbu yo‘nalishdagi ilmiy-tadqiqot ishlarini davom ettirish dolzarb ahamiyatga ega. uning faol jarayonga aylanishini oldini oladi.
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