SURUNKALI BUYRAK KASALLIGI (SBK) BO'LGAN BOLALARNING JISMONIY VA SOMATIK HOLATINI BAHOLASH
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Surunkali buyrak kasalligi, bolalar, o'sishdan orqada qolish, surunkali glomerulyar kasalliklar, siydik tizimining tug’ma nuqsonlari##article.abstract##
Maqsad: SBK bilan kasallangan bolalarning yoshi, kasallikning bosqichi va davomiyligi bilan bog'liq holda o'sish rivojlanishini baholash.
Materiallar va metodlar: Tadqiqot Samarqand viloyat ko‘p tarmoqli tibbiyot markazining nefrologiya bo‘limida 5 yoshdan 18 yoshgacha bo‘lgan 260 nafar, jumladan, surunkali buyrak kasalligi (SBK)ning turli bosqichlarida bo‘lgan 152 nafar o‘g‘il va 108 nafar qiz bolalarda o‘tkazildi. Tadqiqotda umumiy klinik, laboratoriya (gematologik, biokimyoviy), instrumental va statistik tadqiqot usullari qo'llanilgan.
Natijalar: Tadqiqot o’tkazish mezonlari 18 yoshgacha bo'lgan bolalar, dializda bo’lmagan, surunkali glomerulyar kasalliklar, siydik tizimining tug'ma nuqsonlari, GFT qiymati 15 ml / min / 1,73 m2 dan yuqori edi. 5-9 yoshda (n=107) bo'yi o'rtacha 116,3±1,2 sm va og'irligi 20,9±0,4 kg atrofida, GFT darajasi 47,38±1,8 ml/min/1,73 m2, kasallikning davomiyligi 3,72±0,26 yil. Ikkinchi yosh guruhlarida 10-14 yosh (n=119) bo'yi 140,9±0,9 sm va vazni 38,2±0,7 kg ni tashkil etdi. GFT ko'rsatkichlari 49,03±2,3 ml/min/1,73 m2 ni ko'rsatadi, kasallikning davomiyligi 4,82±0,3 yil atrofida. Uchinchi guruh 15-18 yoshli (n=33) bemorlarning bo'yi 163,3±1,6 sm, vazni 61,9±2,1 kg, GFT 57,96±6,3 ml/min/1,73 m2 va kasallikning davomiyligi 5,84±0,7 yil atrofida edi.
Xulosa. SBK bilan og'rigan bolalarning umumiy o’sish va somatik holati kasallikning bosqichi va davomiyligi bilan belgilanadi. Bolalikda SBK o'sishda sezilarli orqada qolishga olib kelishi mumkin ayniqsa 3-5 bosqichda 50% hollarda. Davolanmagan tug'ma nuqson sababli rivojlangan SBK, o'sishdan orqada qolish asosan 5-9 yoshda kuzatiladi.
Библиографические ссылки
Masalskienė J. et al. Epidemiology of chronic kidney disease in children: a report from Lithuania //Medicina. – 2021. – Т. 57. – №. 2. – С. 112.
Aier A., Pais P., Raman V. Psychological aspects in children and parents of children with chronic kidney disease and their families //Clinical and Experimental Pediatrics. – 2021. – Т. 65. – №. 5. – С. 222.
Piccoli G. B. et al. Nutritional status and the risk of malnutrition in older adults with chronic kidney disease–implications for low protein intake and nutritional care: a critical review endorsed by ERN-ERA and ESPEN //Clinical Nutrition. – 2023. – Т. 42. – №. 4. – С. 443-457.
Nelms C. L. et al. Assessment of nutritional status in children with kidney diseases—clinical practice recommendations from the Pediatric Renal Nutrition Taskforce //Pediatric Nephrology. – 2021. – Т. 36. – С. 995-1010.
Xu Y. et al. Factors associated with the absence of pharmacological treatment for common modifiable complications in children with chronic kidney disease //Pediatric Nephrology. – 2021. – Т. 36. – №. 10. – С. 3181-3189.
Муродова М. Д. и др. Оценка ферротерапии у детей с хроническим пиелонефритом //Актуальные аспекты медицинской деятельности. – 2021. – С. 231-235.
Yadin O. Over Three Decades of Growth Hormone Treatment in Children With Chronic Kidney Disease‐Associated Growth Failure Before and After Kidney Transplantation //Pediatric Transplantation. – 2024. – Т. 28. – №. 5. – С. e14803.
Ahmed H. M. et al. The Association Between Markers of Inflammation and the Progression of Chronic Kidney Disease in Children with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) //GEGET. – 2024. – Т. 19. – №. 1. – С. 62-73.
Djamolovna M. M., Axmatovich Y. B., Farkhodovna M. F. Metabolic Characteristics Of The Heart In Children With Chronic Kidney Disease //NVEO-natural volatiles & essential oils Journal| NVEO. – 2021. – С. 8070-8076.
Yuen K. C. J. et al. Growth hormone/insulin-like growth factor I axis in health and disease states: an update on the role of intra-portal insulin //Frontiers in Endocrinology. – 2024. – Т. 15. – С. 1456195.
Aldridge M. K. et al. Effectiveness of growth hormone on growth and final height in paediatric chronic kidney disease //Pediatric Nephrology. – 2022. – С. 1-8.
Todisco T. et al. Chronic Kidney Disease and Growth Failure in Children //Children. – 2024. – Т. 11. – №. 7. – С. 808.
Муродова М. Д., Юлдашев Б. А. Оценка метаболических показателей сердечно-сосудистой системы при нефротическом синдроме у детей //Экспериментальная и клиническая гастроэнтерология. – 2024. – №. 6. – С. 96-100.
Akhmatovich Y. B., Djamolovna M. M. Criteria for cardiovascular disorders in acute nephritic syndrome in children //journal of biomedicine and practice. – 2023. – т. 8. – №. 5.
Voronina T. et al. Study of the effect made by interval hypoxic training on cardiac metabolism and hemodynamics //Cardiometry. – 2021. – №. 20. – С. 8-9.
Rizaev JA, Shamsiev JA, Zayniev SS Ways to Optimize Patient Outcomes and Improve the Quality of Medical Care in Surgically Correctable Congenital Malformations in Samarkand //European Journal of Research Development and Sustainability. – 2021. – T. 2. – No. 3. – pp. 45-48.
