JIGAR SIRROZI BILAN OG‘RIGAN BEMORLARDA ASTSITIK SUYUQLIKNI REINFUZIYA ZARURATINING PATOGENETIK ASOSLARI
##article.subject##:
: astsit suyuqlik, albumin, jigar sirrozi, limfa tizimi.##article.abstract##
Jigar sirrozi jiddiy kasallik bo‘lib, dunyo bo‘ylab o‘limning eng ko‘p uchraydigan sabablari orasida 11-o‘rinda turadi, bemorlarning 50% 5 yil ichida vafot etadi. Sirozdagi astsitlar turli patogenetik omillar natijasida rivojlanadi: giperaldosteronizm, organizmda suyuqlik to‘planishi, portal gipertenziya, limfa ishlab chiqarishning ko‘payishi va chiqishining buzilishi, parietal peritonning drenaj funktsiyasining pasayishi, autoimmun disproteinemiya va plazma kolloid-onkotik muvozanatning buzilishi. Zamonaviy tibbiyot astsitlarni davolashning bir necha usullarini taklif etadi, jumladan dori terapiyasi, katta hajmdagi suyuqlikni olib tashlash bilan seriali laparosentezlar, transyugulyar ichki jigar portosistemik shuntlash, drenaj qurilmalarini implantatsiya qilish, shuningdek hujayrasiz va konsentrlashgan reinfuzion terapiya. Ushbu yondashuvlarning har biri o‘zining afzalliklari va cheklovlariga ega va optimal davolash strategiyasini tanlash ko‘pincha qiyin vazifani keltirib chiqaradi. Ushbu maqolada Fresenius preparati bilan reinfuziya yordamida astsitni davolashning zamonaviy usullari muhokama qilinadi.
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