ЛЮПУС НЕФРИТ РИВОЖЛАНИШИДА TGFb1 ГЕНИНИНГ АХАМИЯТИ
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Ген, люпус нефрит, TGFb1##article.abstract##
Ҳозирги кунда ЛНнинг ривожланишидаги гемодинамик, метаболик ва генетик омилларнинг ахамияти муҳокама қилинмоқда. Айниқса ЛНнинг ривожланишини прогноз қилувчи генетик омилларнинг тутган ўрни катта қизиқиш билан ўрганилмоқда. Аммо ЛН билан оғриган беморларда генларнинг клиник-патогенетик ахамияти ва прогностик роли тўлиқ ўрганилмаган ва ЛН ривожланишига сабаб бўлувчи генетик мойиллик масаласида аниқ бир тўхтам мавжуд эмас.
Библиографические ссылки
Kovalenko VM, Golovach ІYu, Bortkevych OP. Аchievements treatment of systemic lupus erythematosus. Ukrai'ns'kyj revmatologichnyj zhurnal. 2012;(50):16-22.
Krasnova TM. Renal involvement in systemic lupus erythematosus: the present views of its pathogenesis and clinical manifestations and the approaches to its treatment. Sovremennaya Revmatologiya. 2008;(3):18-21.
Makarova TP, Senek SA, Firsova NN, et al. Lupus nephritis: approaches to diagnosis and treatment. Practical medicine. 2008;(31):44-48.
Nasonov EL. New possibilities of pharmacotherapy for systemic lupus erythematosus: A place of belimumab. Sovremennaya Revmatologiya. 2014;(4):4-13. doi: 10.14412/1996-7012-2014- 4-4-13.
Himion LV. The strategy of treatment of lupus nephritis: an overview of current recommendations. Ratsionalnaya farmakoterapiya. 2013;(28):27-31.
Shilov E, Kozlovskaya N. Lupus nephritis: modern therapy. Klinicheskaia nefrologiia. 2010;(1):36-40.
ACCESS Trial Group. Treatment of lupus nephritis with abatacept: the Abatacept and Cyclophosphamide Combination Efficacy and Safety Study. Arthritis Rheumatol. 2014 Nov;66(11):3096-104. doi: 10.1002/art.38790.
Alexander T, Sarfert R, Klotsche J, et al. The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus. Ann Rheum Dis. 2015 Jul;74(7):1474-8. doi: 10.1136/annrheumdis-2014-206016.
Hahn B.H., McMahon M.A., Wilkinson A., et al. American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis. Arthritis Care Res (Hoboken). 2012 Jun;64(6):797-808. doi: 10.1002/acr.21664.
Appel GB, Contreras G, Dooley MA, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J Am Soc Nephrol 2009;20(5):1103-1112. doi: 10.1681/ASN.2008101028.
Ziyadullaev S. K. et al. MARKER TNFα-308G/A IN PATIENTS WITH RELATIVE BLADDER CANCER //Oriental renaissance: Innovative, educational, natural and social sciences. – 2021. – Т. 1. – №. 8. – С. 926-932
Yusupov Mashrab, Rizaev Zhasur, Ziyadullaev Shuxrat. The value of cytokines in children with escherichiosis. Journal of Biomedicine and Practice. 2022, vol. 7, issue 4, pp.58-63