ASSOCIATION BETWEEN CYTOLOGICAL CHARACTERISTICS AND EXPRESSION OF THE CALCA AND ACE GENES IN PATIENTS WITH SIMPLE AND COMPLEX MIGRAINE
Keywords:
Migraine, CALCA and ACE genes, CGRP receptorsAbstract
Migraine remains one of the most common and socially significant neurological disorders, characterized by a high rate of chronification and disability among patients. Despite advances in modern pharmacotherapy, a considerable proportion of patients exhibit resistance to standard treatment approaches. This highlights the need for identifying new biomarkers — both cytological and genetic — that could enable early diagnosis, prediction of therapeutic response, and the development of personalized prevention strategies.
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