IMPACT OF STRESS AND ANXIETY LEVELS ON DISEASE ACTIVITY IN PATIENTS WITH RHEUMATOID ARTHRITIS AND OUTCOMES OF A КОМПЛЕКС MULTIMODAL PSYCHOTHERAPEUTIC APPROACH
Keywords:
rheumatoid arthritis, stress, anxiety, psychotherapy, cognitive-behavioral therapy, disease activity, quality of lifeAbstract
This study focused on assessing the psychoemotional state and quality of life in patients with rheumatoid arthritis and evaluating the effectiveness of a comprehensive psychotherapeutic approach. Anxiety and depressive manifestations and their impact on patients’ general condition were examined. Patients receiving psychological intervention showed improved emotional well-being, reduced pain symptoms, and increased social activity. Quality of life indicators also demonstrated positive changes. Improvements in the standard treatment group were less pronounced. The findings emphasize the importance of considering psychological factors in the management of rheumatoid arthritis.
References
Smolen J.S., Aletaha D., McInnes I.B. Rheumatoid arthritis. Lancet. 2016;388(10055):2023–2038. doi:10.1016/S0140-6736(16)30173-8.
Matcham F., Rayner L., Steer S., Hotopf M. The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis. Rheumatology. 2013;52(12):2136–2148. doi:10.1093/rheumatology/ket169.
Cutolo M., Straub R.H. Stress as a risk factor in the pathogenesis of rheumatoid arthritis. Autoimmunity Reviews. 2014;13(12):1146–1149. doi:10.1016/j.autrev.2014.10.002.
Kojima M., Kojima T., Ishiguro N. Psychosocial factors and quality of life in rheumatoid arthritis. Modern Rheumatology. 2009;19(5):535–542. doi:10.1007/s10165-009-0209-0.
Sharpe L., Sensky T., Timberlake N. Cognitive behavioral therapy for patients with rheumatoid arthritis: long-term outcomes. Pain. 2001;89(2–3):195–203. doi:10.1016/S0304-3959(00)00359-4.
Van Dyke M.M., Parker J.C. Cognitive behavioral therapy for rheumatoid arthritis pain and disability. Arthritis Care & Research. 2012;64(8):1125–1132. doi:10.1002/acr.21666.
Matcham F., Ali S., Irving K. Are depression and anxiety associated with disease activity in rheumatoid arthritis? Rheumatology. 2016;55(5):879–890. doi:10.1093/rheumatology/kev403.
Katz P. Causes and consequences of fatigue in rheumatoid arthritis. Current Opinion in Rheumatology. 2017;29(3):269–276. doi:10.1097/BOR.0000000000000376.
Zautra A.J., Hamilton N.A., Burke H.M. Resilience and chronic arthritis: psychosocial factors and adaptation. Health Psychology. 2010;29(4):389–397. doi:10.1037/a0019725.
Smolen J.S., Landewé R.B.M., Bijlsma J.W.J. et al. EULAR recommendations for the management of rheumatoid arthritis. Annals of the Rheumatic Diseases. 2020;79(6):685–699. doi:10.1136/annrheumdis-2019-216655.
Fiest K.M., Hitchon C.A., Bernstein C.N. Systematic review and meta-analysis of depression in rheumatoid arthritis. Arthritis Care & Research. 2017;69(10):1593–1603. doi:10.1002/acr.23176.
Yusupxodjayeva S.T. Revmatoid artrit patogenezida psixoemotsional buzilishlarning roli va ularni aniqlashning samarali usullari. Oriental journal of medicine and natural sciences 2 (4) 127-131, 2025
