MAIN NEUROLOGICAL SYNDROMES OCCURRING IN BILIRUBIN ENCEPHALOPATHY IN INFANTS AND CHILDREN OF EARLY AGE
Keywords:
bilirubin encephalopathy, neonatal jaundice, cerebral palsy, morbid, nuclear jaundice.Abstract
The pathological course of neonatal jaundice remains an urgent problem in the world today. The nature of accumulation of the main amount of bilirubin in the deep roots of the brain in hyperbilirubinemia has not yet been fully determined. The clinic and prognosis of bilirubin encephalopathy etiology are being studied in depth. As a result of the accumulation of bilirubin, the basal ganglia, hypothalamus, nuclei of the brain stem (e.g. oculomotor, cochlear, vestibular and olivary nuclei) and cerebrum acquire a yellow color. Neonatal jaundice causes morbid and premorbid conditions as a result of acute bilirubin encephalopathy, complicated chorio-athetoid cerebral palsy. A pathological condition resulting from necrosis of neurons and deep yellowing of neurons of the basal ganglia and brainstem nuclei is considered. [1].
References
Correspondence: Tina M Slusher Division of Global Health, Pediatric Intensive Care Faculty, Hennepin County Medical Center, University of Minnesota, 701 Park Ave, G7, Minneapolis, M
Division of Neuropathology, University of Alberta and Stollery Children’s Hospital, Edmonton, AB T6G 2B7, Canada; vanlande@ualberta.ca
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