POLYSOMNOGRAPHIC CHARACTERISTICS OF SLEEP DISORDERS IN CHRONIC BRAIN ISCHEMIA AND THE LEVEL OF MELATONIN IN THE BLOOD

Authors

  • Olmosov Ravshan Sherxon ogli
  • Yakubova Markhamat Mirakramovna
  • Nazarova Nigora Zikrillaevna

Keywords:

chronic cerebral ischemia, melatonin, polysomnography, senile age, dyssomnia

Abstract

Sleep disorders are one of the actual problems of neurology, and the relevance of the problem is determined by the increase in the population of senile age. The paper analyzes the polysomnographic study of examined patients with sleep disorders. In the scientific work, 66 (100%) patients were examined, of which 38 (57.6%) were men, 28 (52.4%) were women. It has been proven that with the progression of the severity of chronic cerebral ischemia, the architectonics of sleep is disturbed in the form of an increase in the representation of the first and second stages of non-REM sleep and a decrease in the third stage and phase of REM sleep. A relationship was also found between the concentration of melatonin in the blood and changes in the architecture of sleep.

References

М.Г.Полуэктов, Диагностика и лечение расстройств сна М.: МЕДпресс-Информ, 12016. - 256 с.

Яковлев Н.А. Хроническая ишемия головного мозга / Н.А. Яковлев, Т.А. Слюсарь, Ю.В. Абраменко.– Тверь: ГЕРС, 2011. – 48 с

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fifth. Arlington,VA: American Psychiatric Association; 2013.

Стрыгин, К. Н. Особенности структуры сна у больных инсомнией с психосоматическими заболеваниями в анамнезе / К. Н. Стрыгин, Е. А.Юматов, Ю. И. Левин // Тез. докл. VI Всеросс. конф.с международн. участием «Актуальные проблемы сомнологии». СПб., 2008. С.92

MimsK. N., KirschD. Sleep and Stroke // SleepMedClin. 2016; 11(1):39-5

Смулевич А. Б., Павлова Л. К., Железнова М. В. Применение препарата Донормил при лечении нарушений сна средней и легкой степени выраженности // РМЖ «Неврология». 2016; № 13:1714–1716

Laakso ML, Porkka-Heiskanen T, Alila A, Stenberg D, Johansson G. Correlation between salivary and serum melatonin: dependence on serum melatonin levels. J Pineal Res. 1990;9(1) 39-50. doi:10.1111/j.1600-079x.1990.tb00692.x. PMID: 2231272.

Öztürk, Güler; Akbulut, Kazime Gonca; And Güney, Şevin (2020) "Melatonin, aging, and COVID-19: Could melatonin be beneficial for COVID-19 treatment in the elderly?," Turkish Journal of Medical Sciences: Vol. 50: No. 6, Article 2. https://doi.org/10.3906/sag-2005-356

Якубова М.М., Олмосов Р.Ш. Бош мия сурункали ишемиясида уйқу бузилишининг ўзига хос полисомнографик кўрсаткичлари// «Неврология» Ташкент. 2020; №4(84): 14-15

Published

2023-06-03