VIRUS ETIOLOGIYALI JIGAR SIRROZI BILAN XASTALANGANLARDA KLINIK VA LABORATOR O`ZGARISHLARNING BOG`LIQLIGI
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virus etiologiyali jigar sirrozi, surunkali gepatit, gepatosellulyar karsinoma, portal gipertenziya##article.abstract##
Jigar sirrozi – keng tarqalgan surunkali avj olib boruvchi jigar kasalligi bo‘lib, diffuz fibroz, psevdobo‘laklarning shakllanishi natijada portal gipertenziya, jigar yetishmovchiligi yoki gepatotsellyulyar karsinoma bilan tavsiflanadi [1]. Jigar sirozining asosiy sabablari gepatit B virusi (HBV) yoki gepatit C virusi (HCV) surunkali infektsiyasi bo'lib, hozirgi davrda butun dunyoda taxminan 296 va 170 million kishiga ushbu kasalliklar bilan zararlangan [2,3]. Ushbu ilmiy tadqiqotda HBV va HCV etiologiyali JSi bilan bemorlarda kasallikning og`irlik darajasiga bog`liq klinik-laborator o`zgarishlari o`rganildi. Tadqiqotga 39 nafar HBV etiologiyali JS va 26 nafar HCV etiologiyali JS bemorlar qatnashdi. Kasallikning o`g`irlik darajasiga bog`liq holda klinik belgilar va laborator diagnostik ko`rsatkichlarda o`zgarishlar qayd etildi [4,5]
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